Anti-ERCC8 Rabbit Polyclonal Antibody (Cy5®)
Product Details & Documents
Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: ERCC8
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Documents
bs-13095R-CY5
Datasheet
Specifications
- Clonality:Polyclonal
- Purification:Purified by Protein A
- Antibody type:Primary
- Form:liquid
- Isotype:IgG
- Storage temperature:Store at 4°C for 12 months
- Host:Rabbit
- Concentration:1 μg/μl
- Cross adsorption:No
- Shipping temperature:4°C
- Antigen name:Excision Repair Cross-Complementation Group 8
- Cat. No.:BOSSBS-13095R-CY5
- Reactivity:Human|Rat|Mouse
- Gene ID:1161
- Antigen synonyms:CSA|UVSS2|CKN1
- Immunogen:180-230/396
- ImmunoChemistry:Yes
- Conjugation:Cy5®
- Antigen symbol:ERCC8
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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