Specifications
- Antibody type:Primary
- Antigen name:Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1
- Antigen symbol:GRINA
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:TMBIM3|NMDA receptor glutamate-binding subunit|LFG1|NMDARA1|GRINA|HNRGW|Protein lifeguard 1
- Storage buffer:Aqueous buffered solution containing 100 μg/ml BSA, 50% glycerol and 0,09% sodium azide. Store at −20 °C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4 °C
- Purification:Purified by Protein A
- Size:100 μg
- Pk:100 µl
Specifications
About this item
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. As one of the four major proteins of the NMDA receptor ion channel, GRINA (Glutamate [NMDA] receptor-associated protein 1), also designated NMDA receptor glutamate-binding subunit or putative MAPK-activating protein PM02, is a 371 amino acid multi-pass transmembrane protein. Due to the chromosomal location of the gene encoding GRINA, studies have linked possible GRINA involvement with a form of idiopathic generalized epilepsy.
Recommended Dilutions: Western Blot: 1:100 to 1000; IHC-P: 1:100 to 500; IF(IHC-P): 1:50 to 200.
Type: Primary
Antigen: GRINA
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat