- Antibody type:Primary
- Antigen name:Signal Transducer And Activator of Transcription 2
- Antigen symbol:STAT2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Gene ID:6773
- Antigen synonyms:IMD44|P113|ISGF-3|signal transducer and activator of transcription 2|STAT113
- Storage buffer:Aqueous buffered solution containing 100 μg/ml BSA, 50% glycerol and 0,09% sodium azide. Store at −20 °C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4 °C
- Immunogen:668-718/851
- Purification:Purified by Protein A
- Size:100 μl
- Pk:100 µl
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Recommended Dilutions: Western Blot: 1:100 to 1000; IHC-P: 1:100 to 500; IF(IHC-P): 1:50 to 200.
Type: Primary
Antigen: STAT2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat