Anti-Synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas and gastrointestinal mucosa. Positive staining is seen in neurons of the brain, spinal cord, retina, and paneth’s cells in the gastrointestinal tract and gastric parietal cells. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. The expression is independent of the presence of NSE or other neuroendocrine markers. Anti-Synaptophysin is an independent broad-range marker of neural and neuroendocrine differentiation.

• Control: Pancreas
• Dilution Range: 1:100-1:500

Pretreatment: Heat induced epitope retrieval in 10 mM citrate buffer, pH 6,0, or in 50 mM Tris buffer pH 9,5, for 20 minutes is required for immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.

Type: Primary
Antigen: SYP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human