Ficin (or Ficain) is a cysteine protease enzyme (EC 3.4.22.3) isolated from fig latex is that has the endopeptidase activity to cleave Immunoglobulin G (IgG) molecules in the hinge region.

• Generate Fab and F(ab‘)₂ fragments
• For digestion of mouse IgG₁
• Eliminates contamination by Ficin