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Supplier: PROMOCELL

Primary Human Dermal Microvascular Endothelial Cells (HDMEC) are isolated from the dermis of juvenile foreskin and adult skin (different locations). Since the dermis contains blood and lymphatic capillaries, HDMEC comprise Blood and Lymphatic Microvascular Endothelial Cells. Both have a common origin and can be identified by several markers.

Supplier: PROMOCELL

Primary Human Umbilical Artery Endothelial Cells (HUAEC) are isolated from the arteries of the umbilical cord and are often used for in vitro studies on atherosclerosis but also for endothelial cell-dependent lymphocyte activation and chemoattractant activity experiments.

Supplier: PROMOCELL

PromoCell Mononuclear Cells (MNC) represent the lymphocyte and monocyte fraction isolated from umbilical cord blood or peripheral blood.

Supplier: PROMOCELL

Primary human chondrocytes (HCH) are isolated from normal human articular cartilage from the knee and hip joints. HCH are routinely tested for the capacity to differentiate in 3D spheroids.

Supplier: PROMOCELL

Primary Human White Preadipocytes (HWP) are isolated from adult subcutaneous or visceral adipose tissue from different locations (lot specific source information is available on request). Adipose tissue is crucial in energy storage and metabolic homeostasis. An increase in adipose tissue results either from an enlargement of mature adipocytes or from the differentiation of adipocyte precursor cells (preadipocytes) into new mature adipocytes. These preadipocytes are already present in adipose tissues. They can proliferate throughout adult life and replace the cells that have differentiated into mature adipocytes.

Supplier: PROMOCELL

Primary Human Uterine Microvascular Endothelial Cells (HUtMEC) are isolated from the myometrium (middle layer of the uterine wall) from a single donor who is not pre-treated with hormones. The cells are routinely analysed by immunofluorescent staining: they stain positive for CD31 and von Willebrand factor and negative for smooth muscle alpha-actin.

Supplier: PROMOCELL

Primary human cardiac fibroblasts (HCF) are isolated from the ventricles of an adult heart. HCF play a central role in the maintenance of the extracellular matrix in the normal heart and the synthesis of growth factors and cytokines.

Supplier: PROMOCELL

Primary human osteoblasts (HOB) are isolated from femoral trabecular bone tissue from the knee or hip joint region. They stain positive for alkaline phosphatase and can be mineralised using mineralisation medium.

Supplier: PROMOCELL

Primary Human Pulmonary Fibroblasts (HPF) are isolated from human lung tissue

Supplier: PROMOCELL

Pericytes are multipotent mesenchymal-like cells found in association with small blood vessel walls and are important for angiogenesis, the structural integrity of the microvasculature and blood flow regulation. However, they can also develop into malignant tumours called hemangiopericytomas.

Supplier: PROMOCELL

Primary normal human epidermal keratinocytes (NHEK) are available from single or pooled donors isolated from the epidermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen and the thighs.

Supplier: PROMOCELL

Primary Human Tracheal Smooth Muscle Cells (HTSMC) are isolated from the trachea from single donors and stain positive for smooth muscle α-actin. They connect the endings of the tracheal cartilage by a contractile bridge called the paries membranaceus and consequently regulate the airway lumen.

Supplier: PROMOCELL

Primary human uterine fibroblasts (HUF) are isolated from the uterine wall.

Supplier: PROMOCELL

Primary Normal Human Epidermal Melanocytes (NHEM) are isolated from the epidermis of juvenile foreskin or adult skin from different locations including the face, the breasts, the abdomen, and the thighs.

Supplier: PROMOCELL

Primary normal human dermal fibroblasts (NHDF) are isolated form the dermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs.

Supplier: STEMCELL Technologies

Custom-designed single guide RNA for CRISPR-Cas9 genome editing.

Supplier: PROMOCELL

Primary Human Aortic Adventitial Fibroblasts (HAoAF) are isolated from human aortic adventitial tissue. HAoAF can be used for studies concerning vascular diseases e.g. neointimal formation, vascular remodeling, atherosclerosis, and hypertension. They are also often used for the examination of fibroblast disorders like fibrosis or other diseases linked to either imperfect or excessive accumulation of fibroblasts.