You searched for: Phorbol-12-myristate-13-acetate

Supplier: Apollo Scientific

This is the most commonly used phorbol ester.  It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues, and is a very potent mouse skin tumor promoter. Crit. Rev. Toxicol. 8:  153-197 (1980)

Supplier: Thermo Fisher Scientific

CAS No.: 16561-29-8

Supplier: Enzo Life Sciences

PKC activator (10 to 100 ng/ml).

Supplier: Abcam

Phorbol 12-myristate 13-acetate (PMA), PKC activator is a potent nanomolar activator of protein kinase C in vivo and in vitro. Binds to C1 domain of protein kinase C, induces membrane translocation and enzyme activation. Also reported to have actions on non-kinase proteins including chimaerins, RasGRP and Unc-13/Munc-13. Extremely potent mouse skin tumour promoter. Cited in over 45 publications - Purity 99% - Supplied in DMSO (10 mM).

Supplier: Abcam

Cell-permeable, selective, non-competitive, potent γ-secretase inhibitor (IC₅₀ =0,3 nM). Active in vitroand in vivo.

Supplier: Thermo Fisher Scientific

Phorbol-12-myristate-13-acetate 95%