Specifications
- Antigen name:Vitamin K epoxide reductase complex subunit 1
- Antigen symbol:VKORC1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western blot:Yes
- Antigen synonyms:IMAGE3455200|MST576|VKOR|MSTP576|EDTP308|VKORC1|Vitamin K1 2|UNQ308/PRO351|3-epoxide reductase subunit 1|VKCFD2|Vitamin K epoxide reductase complex subunit 1|MST134|MSTP134
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:VKORC1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human VKORC1.
- Tested applications:E, WB, IHC, IF
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
Specifications
About this item
VKORC1 Antibody: Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.
Type:
Antigen: VKORC1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse