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Anti-RENT1/hUPF1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-RENT1/hUPF1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-8565R-A750
Supplier:  Bioss
Anti-RENT1/hUPF1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-8565R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    RENT1/hUPF1
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Epitope:
    301-450/1129
  • Form:
    Liquid
  • Gene ID:
    5976
  • Antigen synonyms:
    KIAA0221|Up framesht mutation 1 homolog|ATP-dependent helicase RENT1|Smg 2 homolog nonsense mediated mRNA decay factor|Regulator of nonsense transcripts 1|Nonsense mRNA reducing factor 1|NORF1|Smg 2|ATP dependent helicase RENT1|Delta helicase|pNORF1|pNORF 1|Up framesht mutation 1 homolog S. cerevisiae|RENT1_HUMAN|UPF1|HUPF1|UP Framesht 1|RENT 1|NORF 1|Up-framesht suppressor 1 homolog|RENT1|UPF 1 regulator of nonsense transcripts homolog|HUPF 1|UPF 1|Up framesht suppressor 1 homolog|Up-framesht mutation 1 homolog S. cerevisiae
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    124 kDa
  • Storage temperature:
    Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human RENT1/hUPF1
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

In eukaryotes, it is essential to have the ability to detect and degrade transcripts that lack full coding potential. Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential. Rent1, a mammalian ortholog of Upflp, is essential for embryonic viability (13). Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase.

Type: Primary
Antigen: RENT1/hUPF1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 301-450/1129
Host: Rabbit
Isotype: IgG
Reactivity: Others