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Anti-SHC Tyr317 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anti-SHC Tyr317 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-3413R-A680
Supplier:  Bioss
Anti-SHC Tyr317 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-3413R-A680
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    SHC Tyr317
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Western blot:
    Yes
  • Form:
    Liquid
  • Gene ID:
    6464
  • Antigen synonyms:
    p46|Shc|SHC A|SHC Src homology 2 domain containing transforming protein 1|p52|Src homology 2 domain containing transforming protein C1|p66 SHC|SH2 domain protein C1|SHC 1|SHC1|p66SHC|SHC transforming protein 1|p52 SHC|SHC transforming protein|p52SHC|p66|SHCA
  • Modification:
    Phosphorylation (Tyr317)
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    63 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from human SHC around the phosphorylation site of Tyr317
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

The SHC gene encodes for a signaling and transforming protein containing Src homology 2 and 3 (SH2 and SH3) domains. The SHC gene encodes 2 widely expressed overlapping proteins of 46 and 52 kD, both containing a C-terminal SH2 domain. Adjacent to the SH2 region is a glycine and proline rich region. These 2 proteins differ in their N terminals. SHC proteins are involved in mitogenic signal transduction and act by coupling growth factor receptors to the RAS signaling pathway. The protein encoded by the SHC1 gene is thought to act as an adaptor in many signal transduction pathways.

Type: Primary
Antigen: SHC Tyr317
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human