Specifications
- Antibody type:Primary
- Antigen name:HEAB
- Clonality:Polyclonal
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:1-100/425
- Form:Liquid
- Gene ID:10978
- Antigen synonyms:ATP/GTP binding protein|Pre-mRNA cleavage complex II protein Clp1|CLP1 cleavage and polyadenylation factor I subunit homolog|Pre mRNA cleavage complex II protein Clp1|clp1|CLP 1|hClp1|Homolog of yeast CFIA subunit Clp1p|CLP1, yeast, homolog of|Polynucleotide kinase Clp1|CLP1, cleavage and polyadenylation factor I subunit, homolog S, cerevisiae|CLP1_HUMAN
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:48 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human HEAB
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilising magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D; mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.
Type: Primary
Antigen: HEAB
Clonality: Polyclonal
Clone:
Conjugation: FITC
Public Immunogen Range: 1-100/425
Host: Rabbit
Isotype: IgG
Reactivity: