Specifications
- Antibody type:Primary
- Antigen name:HCCS
- Clonality:Polyclonal
- Conjugation:Cy3®
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat,Mouse
- Epitope:51-150/268
- Form:Liquid
- Gene ID:3052
- Antigen synonyms:Holocytochrome c type synthase|OTTHUMP00000022905|CCHL_HUMAN|OTTMUSP00000021173|OTTHUMP00000022903|CCHL|Holocytochrome c synthase cytochrome c heme lyase|RGD1563855|RP23-37L2,1|OTTHUMP00000022904|DKFZp779I1858|EC 4,4,1,17|OTTMUSP00000021174|MCOPS7
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:31 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human HCCS
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
HCCS is a 79 amino acid protein that may act as a tumor suppressor, promoting the apoptosis of cancer cells. Expressed in leukocytes, lung, spleen, liver, heart, kidney, muscle and uterine cervix, HCCS-1 is down-regulated in cervical cancers. The gene encoding HCCS-1 maps to human chromosome 15q25.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
Type: Primary
Antigen: HCCS
Clonality: Polyclonal
Clone:
Conjugation: Cy3
Public Immunogen Range: 51-150/268
Host: Rabbit
Isotype: IgG
Reactivity: Mouse; Rat