400 Results for: "odmab"

Supplier: ProSci Inc.

JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

Supplier: US Biological

Anti-KDM4B Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Supplier: Novus Biologicals

Anti-KDM6B Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Novus Biologicals

Anti-KDM6B Rabbit Polyclonal Antibody (DyLight® 550)

Supplier: Abcam

Mouse monoclonal [H2Mab-139] to ErbB2 / HER2.

Supplier: US Biological

Anti-KDM4B Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Supplier: US Biological

Anti-KDM4B Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Supplier: US Biological

Anti-KDM4B Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Supplier: US Biological

Anti-KDM1B Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Supplier: Abcam

Rabbit recombinant multiclonal [RP23040274] to KDM4B/JMJD2B.

Supplier: US Biological

Anti-KDM3B Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: US Biological

Anti-KDM5B Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Supplier: US Biological

Anti-KDM6B Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: Abcam

Rabbit monoclonal [EPR25242-12] to KDM5B/PLU1/Jarid1B.

Supplier: Bioss

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).

Supplier: Bioss

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).

Supplier: Bioss

JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.

Supplier: Bioss

ODF3B, also known as ODF3L3 (outer dense fiber protein 3-like protein 3), is a 253 amino acid protein belonging to the ODF3 family. Existing as two isoforms produced by alternative splicing, ODF3B contains one DUF1309 repeat. The gene that encodes ODF3B maps to human chromosome 22, which contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia.

Supplier: US Biological

Anti-KDM2B Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-KDM3B Rabbit Polyclonal Antibody

Supplier: Biorbyt

Anti-ODF3B Rabbit Polyclonal Antibody

Supplier: OriGene

Anti-KDM3B Rabbit Polyclonal Antibody

Supplier: Abnova

Rabbit polyclonal antibody raised against partial recombinant Kdm4b.

Supplier: OriGene

Anti-KDM6B Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-KDM4B Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-Kdm6b Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100

Supplier: Abnova

Rabbit polyclonal antibody raised against synthetic peptide of KDM6B.

Supplier: Biorbyt

Anti-KDM4B Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.