Supplier: Bioss

IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Supplier: Bioss

IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Supplier: GRANT INSTRUMENTS

The Grant Optima™ range consists of both general purpose and advanced performance thermostats combined with premium stainless steel baths (drain tap on 12, 18, 26 and 38 litre baths). Stirred circulation within the bath ensures excellent temperature stability and uniformity. Units can also be used with accessory C1G and C2G immersion coolers for operation below ambient temperatures.

Supplier: Portwest

The DX4 Baffle Gilet uses a body-mapped design to balance insulation and freedom of movement. Hard-wearing nylon front and back panels are padded with Insulatex to keep the core body area warm. Two zipped chest pockets, side entry pockets, and internal pockets offer plenty of secure storage space.

Supplier: Thermo Fisher Scientific

Use Thermo Scientific™ SureSTART™ 9 mm screw caps with screw vials that have a 9 mm opening, including our SureSTART 2 ml glass screw vials and 1,7 ml glass high recovery screw microvials for <2 ml samples (level 2). Select level 2 products for high-throughput applications, when robustness and reproducibility are key.

Supplier: Thermo Fisher Scientific

SureSTART™ Level 3 WebSeal™ Plate 96-well round U, V, and flat-bottom microtiter plates are designed for regulated labs that require high performing products. Level 3 well plates are for high performance applications and are suitable for regulated labs using all solvent types including non-polar solvents.

Supplier: SIOEN

Wind- and waterproof bodywarmer made of Flexothane® Classic: 100% polyamide knitting with PU coating. With fixed quilted lining.

Supplier: SIOEN

Comfortable, modern jacket made of 100 % quilted polyamide fabric with soft fleece lining inside and polyamide lining in the sleeves. Offers protection from wind and cold. Can be zipped in the rain jacket Tornhill (608).

Supplier: FRISTADS KANSAS

Protective trousers made from 75% cotton and 25% polyester. The cotton/polyester fabric mix offers long lasting protection against open flames and sources of heat thanks to the flame-retardant used.

Supplier: Portwest

Portwest WX3 contemporary workwear is designed to the highest standards and offer a solution for everyday activity and working environments. Constructed with cutting edge fabrics giving superior abrasion resistance and exceptional all-day comfort. The WX3 work trousers are made from durable poly-cotton canvas fabric and includes triple stitched seams and stretch panelling providing excellent comfort and flexibility.

Supplier: Portwest

The Vision softshell is characterised by its modern, fresh design and contemporary stylish fit. The high quality 3-layer breathable, water resistant and windproof fabric along with multiple practical features ensure this is a must-have solution for a range of working professionals.

Supplier: KIMBLEKONTES

Soda lime glass, 90 expansion.

Supplier: SIOEN

Waterproof and windproof rain jacket made of Flexothane Classic: 100% polyamide knitting with 100% PU coating. With high frequency welded seams.

Supplier: Sartorius Balances

The modular weighing system Cubis® II can be individually configured from different components. The combinability of the display unit, weighing module, draft shield, software packages for various applications and functions and a comprehensive range of accessories allows the individual adaptation of the Cubis® II balance to all weighing tasks.

Supplier: BIOTIX

xTIP4™ is the only Rainin® LTS® compatible tip engineered with StarStop, a patented positive stop feature. This feature minimizes ejection force and reduces the risk of repetitive stress injuries (RSI).

Supplier: Liebherr

The refrigerators with spark-free interior are easy to clean and the robust glass shelves are simple to remove at 90° door opening. They are super-efficient, utilising the energy-savings potential of every component.

Supplier: VWR Collection

VWR® has expanded the VWR® carboy features and benefits by offering the Versatile Cap, Versatile Barb and state-of-the-art Spigot technology. These three components complement a wide array of applications supported by the VWR® Carboy. The leakproof cap insert with replaceable gasket enable users to quickly change the top connector of each carboy to match the application needs. Versatile Cap is stackable and is offered in both 83 mm (compatible with most industry carboys) and a 120 mm extra wide-mouth version that fits exclusively on VWR® 20 L and 40 L extra wide mouth carboys. To see homogenisation of solutions, closed adapter inserts with a clear window are available. Quick connect options are also a part of the many capabilities of this Versatile Cap technology. This includes quick-connect port combinations of two, three, and four. For bottom tubulation, Versatile Barb is used to replace the spigot and support flexibility in drainage, connection to a pump or automated equipment, or connection to a filling bell. Sanitary fitting connector is also available in order to enable the carboy to be used as a supply reservoir to a larger system.

Supplier: Bioss

Comprising more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to APC and activates APC’s cyclin-ubiquitination activity. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC; thus preventing APC activation. APC11 is a RING-H2 finger protein that allows for the synthesis of multiubiquitin chains in the presence of Ubiquitin carrier protein 4 (Ubc4) and ubiquitin conjugating enzyme (E2). In addition, a heterodimeric complex of either Ubc4 or UbcH10 with APC11 and APC2 catalyzes the ubiquitination of human securin and cyclin B1.

Supplier: CONTEC

Improved, versatile, multiple bucket system for use with flat and curved Contec® mops.

Supplier: HELLMA

Hellma® high precision quartz glass macro cells for absorption measurements in the UV/Vis/NIR range, 1 to 50 mm path length, with stopper.

Supplier: Ansell

RINGERS^® R840 light-duty impact-resistant gloves feature a low profile level 1 TPR (Thermoplastic Rubber) impact technology providing optimal protection to the knuckles, thumb and full length of fingers.

Supplier: HELLMA

Hellma® high precision quartz glass (macro-) cylinder cells for absorption measurements in the UV/Vis/NIR range, 0,1 to 100mm path length, with stopper.

Supplier: LABCONCO

FreeZone® bench top freeze dryers are designed for lyophilising light to moderate sample loads. The compact design is ideal for laboratories with limited floor space.

Supplier: CONTEC

VertiKlean® MAX™ is designed for applying disinfectants to both horizontal and vertical surfaces and is ideal for general cleaning of ceilings, walls and floors. This lightweight mop features a single layer of hydrophilic polyurethane foam laminated to polyester microfibre fabric backed with a semi-rigid thermoformed plate, which easily snaps onto a VertiKlean® mop head frame.

Supplier: Bioss

Comprising more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to APC and activates APC’s cyclin-ubiquitination activity. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC; thus preventing APC activation. APC11 is a RING-H2 finger protein that allows for the synthesis of multiubiquitin chains in the presence of Ubiquitin carrier protein 4 (Ubc4) and ubiquitin conjugating enzyme (E2). In addition, a heterodimeric complex of either Ubc4 or UbcH10 with APC11 and APC2 catalyzes the ubiquitination of human securin and cyclin B1.

Supplier: DuPont

These unhooded coveralls, model IC183BWH TS, are made of Tyvek®, a fabric composed of flash spun high density polyethylene, providing an ideal balance of protection, durability, and comfort. Tyvek® is permeable to both air and water vapour, yet repels water-based liquids and aerosols. It offers an excellent barrier against fine particles and fibres (down to 1 µm in size).

Supplier: DuPont

These hooded coveralls, model IC193BWH TS, are made of Tyvek®, a fabric composed of flash spun high density polyethylene, providing an ideal balance of protection, durability and comfort. Tyvek® is permeable to both air and water vapour, yet repels water-based liquids and aerosols. It offers an excellent barrier against fine particles and fibres (down to 1 µm in size).

Supplier: Thermo Fisher Scientific

Armadillo™ 384-well PCR plates combine the rigidity of a polycarbonate frame with thin walled polypropylene wells to provide superior thermal cycling performance under all conditions, without warping. All formats are available with clear or white wells, ensuring the highest level of sensitivity for all PCR and qPCR reactions.

Supplier: Bioss

IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Supplier: Thermo Fisher Scientific

Meet your certification and documentation needs with our level 2 Thermo Scientific™ SureSTART™ specification certified screw vial and cap kits. Select level 2 products for high throughput applications, when robustness and reproducibility are key.