1627 Results for: "TMC HALLCREST"
Isotetrandrine ≥98% (by TLC)
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Phospholipase inhibitor
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5-Iodotubercidin ≥98% (by TLC)
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Inhibits ERK2 (Ki = 525nM). Also inhibits adenosine kinase (Ki = 30nM), CK1 and CK2 and insulin receptor kinase (IC50 ranging from 0.4-28µM).
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AACOCF3 ≥98% (by TLC)
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AACOCF3 is a trifluoromethylketone derivative of arachidonic acid. It is a selective inhibitor of human cytosolic PLA2 and Ca2+-independent PLA2 (iPLA2, IC50=15 µM). It is active in intact platelets and U937 cells (IC50=8 µM). It also inhibits fatty acid amide hydrolase (100% at 7.5 µM).
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H-Arg-AMC·2HCl
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Substrate for cathepsin H and aminopeptidases
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HBDDE ≥95% (by TLC)
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Inhibits PKCα (IC50=43 µM) and PKCγ (IC50=50 µM) without inhibiting the δ, βI and βII isotypes.
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Apigenin ≥97% (by TLC)
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Antioxidant and chemopreventive
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Latrunculin A ≥98% (by TLC)
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Ultra-pure; inhibits actin polymerization
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BMOV ≥96% (by TLC)
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Organic vanadium complex which acts as a potent insulin mimic.
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Anandamide ≥98% (by TLC)
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Endogenous [1] ligand for the CB1 receptor (CB1: Ki=52nm; CB2: Ki=1930nm [2]) and TRPV1 (Ki=5.78µM [3,4]). Inhibits NF-κB activation through direct binding to IKKβ [5] and induces apoptosis independently of cannabinoid or vanilloid receptors [6]. Activates the MAP kinase (MAPK/ERK) signalling pathway [7].
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Ilimaquinone ≥98% (by TLC)
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ADP-ribosylation factor inhibitor
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L-744,832 ≥98% (by TLC)
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Ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expression and arrests cells at G1. Causes enhanced mitotic sensitivity to taxol.
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Palmitoylethanolamide ≥98% (by TLC)
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Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
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Calpeptin ≥98% (by TLC)
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Calpain and cathepsin inhibitor
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Virodhamine ≥98% (by TLC)
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Cannabinoid receptor ligand.
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CCT036477 ≥98% (by TLC)
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Disrupts Wnt signaling
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H-9 HCl ≥98% (by TLC)
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An excellent affinity ligand for chromatographic purification of protein kinases. Inhibits protein kinases (Ki's: PKA=1.9 µM; PKC=18 µM; PKG=0.87 µM; MLCK=70 µM).
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Forskolin ≥99% (by TLC)
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Adenylate cyclase activator
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Calyculin A ≥98% (by TLC)
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Inhibitor of PP1 and PP2A
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4-Hydroxyphenylretinamide ≥97% (by TLC)
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Retinoic acid receptor ligand.
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Supplier: Integra
Supplier: EPPENDORF
Supplier: Integra
Supplier: OZ BIOSCIENCES
Supplier: VWR Collection
Supplier: Corning
Supplier: SenseAnywhere
Supplier: NANOENTEK
Supplier: VWR Collection
Supplier: Integra
Supplier: Testo
Supplier: Sartorius
Supplier: SenseAnywhere
Supplier: Quantabio