1627 Results for: "TMC HALLCREST"
N-Arachidonylglycine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
FAAH inhibitor
Expand 1 Items
α-Hydroxyalprazolam ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Metabolite of alprazolam.
Expand 1 Items
Chaetocin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Methyltransferase inhibitor
Expand 1 Items
U-75302 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Prostanoid receptor ligand.
Expand 1 Items
H-7 dihydrochloride ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.
Expand 2 Items
Apigenin ≥97% (by TLC)
Supplier: ENZO LIFE SCIENCES
Antioxidant and chemopreventive
Expand 2 Items
Calpeptin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Calpain and cathepsin inhibitor
Expand 2 Items
L-744,832 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expression and arrests cells at G1. Causes enhanced mitotic sensitivity to taxol.
Expand 1 Items
Anandamide ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Endogenous [1] ligand for the CB1 receptor (CB1: Ki=52nm; CB2: Ki=1930nm [2]) and TRPV1 (Ki=5.78µM [3,4]). Inhibits NF-κB activation through direct binding to IKKβ [5] and induces apoptosis independently of cannabinoid or vanilloid receptors [6]. Activates the MAP kinase (MAPK/ERK) signalling pathway [7].
Expand 2 Items
BMOV ≥96% (by TLC)
Supplier: ENZO LIFE SCIENCES
Organic vanadium complex which acts as a potent insulin mimic.
Expand 1 Items
Latrunculin A ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Ultra-pure; inhibits actin polymerization
Expand 2 Items
Ilimaquinone ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
ADP-ribosylation factor inhibitor
Expand 1 Items
Palmitoylethanolamide ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
Expand 1 Items
Virodhamine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cannabinoid receptor ligand.
Expand 1 Items
Monastrol ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
Expand 2 Items
(S)-Mephenytoin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cytochrome P450 substrate.
Expand 2 Items
2',5'-Dideoxyadenosine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Adenylate cyclase inhibitor
Expand 2 Items
Dorsomorphin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.
Expand 2 Items
Bisindolylmaleimide I ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
Expand 2 Items
Kifunensine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits α-mannosidase. Inhibits asparagine-linked oligosaccharide processing. Immunomodulator.