63060 Results for: "Pipety+graduované&pageNo=50&view=easy"
Human recombinant IL20 (fromE. coli)
Supplier: ProSci Inc.
Interleukin-20 (IL-20) is a member of the IL-10 family of regulatory cytokines that includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 exhibits approximately 28% amino acid identity with IL-10 and 76% amino acid identity with mouse IL-20. There are two heterodimeric receptor complexes for IL-20. The first is composed of IL-20 R alpha and IL-20 R beta . The second is composed of IL-22 R and IL-20 R beta . Whereas the IL-22 R/IL-20 R beta complex is shared with IL-24, the IL-20 R alpha/IL-20 R beta complex is shared with both IL-19 and IL-24. IL-20 has been shown to initiate transduction cascades involving STAT3 and stimulates the induction of pro-inflammatory genes including TNF- alpha and MCP-1. Initial functional studies using transgenic mice suggest that IL-20 has the ability to regulate skin development. The over-expression of both human and mouse forms of IL-20 results in keratinocyte hyper-proliferation, abnormal epidermal differentiation, and neonatal lethality. In humans, IL-20 and its receptors are up-regulated in psoriatic skin, and polymorphisms in the IL-20 gene have been associated with plaque-type psoriasis. IL-20 may also have a role in hematopoiesis. It enhances the proliferation of multi-potential progenitors in vitro and increases their numbers and cell cycling status in IL-20 transgenic mice. IL-20 is also shown to suppress COX-2 and PGE2 and acts as an inhibitor of angiogenesis in model systems.
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SEPCAP INJECTOR CLEAR VIAL NATURAL POLYETHELYNE CAP 1 * 1.000 items
Supplier: THERMO NATIONAL SCIENTIFIC
SEPCAP INJECTOR CLEAR VIAL NATURAL POLYETHELYNE CAP 1 * 1.000 items
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calibrate with certificate 1 * 1 items
Supplier: HAMILTON BONADUZ
calibrate with certificate 1 * 1 items
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SPRING MICRO TIP 50µL. 200µL. 1 * 1 items
Supplier: Socorex Isba
SPRING MICRO TIP 50µL. 200µL. 1 * 1 items
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Test strips, peroxide, QUANTOFIX®
Supplier: MACHEREY-NAGEL
QUANTOFIX® test strips meet all requirements of a modern rapid test. The colour of the reactive pad changes depending on the concentration of an analyte in the sample. The evaluation is usually carried out visually by comparison of the reaction colour with a multi-stage colour scale. These test strips are immediately ready-to-use. They do not require additional accessories. The test strips are intended for single use, maintenance or calibration are not required.
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Intrinsic factor (from porcine pyloric mucous lining), powder
Supplier: MP Biomedicals
Preparation Method: MP Intrinsic Factor is produced from the pylorus mucous membrane of the pig, of which only a small part is used. Only the part which, according to histological examinations has proved to have a high content of Intrinsic Factor, is used.
Applications: Intrinsic Factor is used in the treatment not only of classical pernicious anaemia, but also in the treatment of other macrocytic anaemias, where it replaces the Intrinsic Factor which may be lacking in the patient's own gastric juice. In this way Intrinsic Factor is recommended against anaemias that appear 6 to 12 months after serious gastric operations, and against anaemias that are secondary effects of the treatment with certain medicines, e.g. against epilepsy. However, the dietetic use in multi-vitamin preparations is of the greatest importance. In older people there has been observed a degeneration of the gastric mucous membrane, whose secretion of Intrinsic Factor is insufficient to ensure the resorption of the necessary quantity of B-12 from their diet. In order to delay this development it is useful to prescribe a small quantity of Intrinsic Factor with B-12 and other vitamins to these patients.
Product Description: Intrinsic factor is a glucoprotein extracted from the pylorus part of the gastric mucous membrane. Its presence is considered necessary for the absorption of Vitamin B-12.
Unit Definition: The activity is normally indicated in Coli units, the number of which are proportional to the binding power of the substance to Vitamin B-12.
Application Areas: Absorption of vitamin B12
Product Type: Proteins, Enzymes & Peptides
Presentation: Tan Powder
Foreign activity: Salmonella=Negative, E. coli=Negative
NOTES: Standard Plate Count <1000/g
Solubility: Slightly soluble in toluene; practically insoluble in water.
Storage & Handling: -20°C
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Mouse recombinant IL36 alpha (from E. coli)
Supplier: ProSci Inc.
Mouse Interleukin-36 alpha(Il-36a)is a member of the IL-1 family.IL¬1 alpha,IL¬1 beta and IL-18 are potent inflammatory cytokines whose activities are dependent on heterodimeric receptors of the IL-1R superfamily, and which are regulated by soluble antagonists. Il36a is expressed in many cells, including monocytes, B cells, and T cells, immune system and fetal brains. Il36a is a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. It is a part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. It seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T cells to drive tissue infiltration, cell maturation and cell proliferation. It Induces the production of proinflammatory cytokines, including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23 in bone marrow-derived dendritic cells (BMDCs). Moreover, it is involved in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II and can induce the production of IFN-gamma, IL-4 and IL-17 by cultured CD4+ T cells and splenocytes. Il36a may play a role in proinflammatory effects in the lung: induces the expression of CXCL1 and CXCL2 in the lung, and the expression of TNF-alpha, IL-36c, IL-1A, IL-1B, CXCL1 and CXCL2 in isolated splenic CD11c+ alveolar macrophages. It may be involved in T cell maturation by stimulating the surface expression of CD40 and modestly CD80 and CD86 in splenic CD11c+ cells and CD4+ T cell proliferation.
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Viscometer-Therm., similar Vogel-Ossag, similar DIN 12785, +90+150:0,2°C, enclosed scale, capillary tube specially coated inside, w ith non-wetting blue special liquid, 470mm long, lower part solid stem 200x5mm, 208mm immersion, Richter-top finish, null
Supplier: Amarell
Viscometer-Therm., similar Vogel-Ossag, similar DIN 12785, +90+150:0,2°C, enclosed scale, capillary tube specially coated inside, w ith non-wetting blue special liquid, 470mm long, lower part solid stem 200x5mm, 208mm immersion, Richter-top finish, null
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BOTTLE CAP SEAL 50ML 1 * 800 items
Supplier: DELTALAB
BOTTLE CAP SEAL 50ML 1 * 800 items
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DISCOVERY DSC-18, 100 GRAM 1 * 100 g
Supplier: Merck
DISCOVERY DSC-18, 100 GRAM 1 * 100 g
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ADHESIVE TAPE 55M WHITE 1 * 12 items
Supplier: DELTALAB
ADHESIVE TAPE 55M WHITE 1 * 12 items
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NANOCOLOR® VARIO Heating Blocks
Supplier: MACHEREY-NAGEL
NANOCOLOR® VARIO C2 has 12 bores for 16 mm Ø test tubes. NANOCOLOR® VARIO HC features a cooling system for active rapid cooling after digestion. The unit has 12 bores for 16 mm Ø test tubes allowing simultaneous digestion of 12 samples and its heating unit includes and aerator, allowing users to digest all important parameters in just 30 minutes.
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L(+)-Lysine monohydrochloride ≥98.5% FCC
Supplier: Spectrum Chemical
L-Lysine Monohydrochloride, FCC - The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
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Human recombinant Galectin 3 (from E. coli)
Supplier: ProSci Inc.
The Galectin family of proteins (with specificity for Nacetyllactosamine containing glycoproteins) consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). At least 14 mammalian galectins family members that share structural similarities in their carbohydrate recognition domains (CRD) have been identified to date. Unlike the selectin family of proteins, the carbohydrate binding specificity of galectins is calcium-independent. A common function of galectins is to cross-link structures containing N-acetyl-lactosamine located at the cell surface and within the extracellular matrix. They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. They have diverse effects on many cellular functions including adhesion, migration, polarity, chemotaxis, proliferation, apoptosis, and differentiation. Galectins may therefore play a key role in many pathological states, including autoimmune diseases, allergic reactions, inflammation, tumor cell metastasis, atherosclerosis, and diabetic complications. The galectins have been classified into the prototype galectins (1, 2, 5, 7, 10, 11, 13, 14), which contain one CRD and exist either as a monomer or a noncovalent homodimer. The chimera galectins (Galectin3) containing one CRD linked to a nonlectin domain, and the tandem repeat Galectins (4, 6, 8, 9, 12) consisting of two CRDs joined by a linker peptide. Galectins lack a classical signal peptide and can be localized to the cytosolic compartments where they have intracellular functions. However, via one or more as yet unidentified nonclassical secretory pathways, galectins can also be secreted to function extracellularly. Individual members of the galectin family have different tissue distribution profiles and exhibit subtle differences in their carbohydrate-binding specificities. Each family member may preferentially bind to a unique subset of cell surface glycoproteins.
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NANOCOLOR® Spectrophotometers
Supplier: MACHEREY-NAGEL
NANOCOLOR® with high-class technology and reference detector technology (RDT) optics can work on smartphones or tablets and an icon-based menu.
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QUANTOFIX CHLORINE 500 TEST STRIPS 1 * 100 Tests
Supplier: MACHEREY-NAGEL
QUANTOFIX CHLORINE 500 TEST STRIPS 1 * 100 Tests
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Needle Regular point 12° Smaller tip diameter 1 * 5 items
Supplier: Hospidex
Needle Regular point 12° Smaller tip diameter 1 * 5 items
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Plasmid isolation, single-strand phage DNA, M-13 isolation kits, E.Z.N.A.® and E-Z 96®
Supplier: OMEGA BIO-TEK
E.Z.N.A.® M13 DNA kits are designed to purify up to 10 μg of single-stranded DNA from up to 3 ml of phage supernatant. Yields of single-stranded DNA obtained using E.Z.N.A.® M13 DNA kits are around 3 to 10 μg and reproducible when the isolations are performed from the same culture. Kits are also available in E-Z 96® DNA plate format.
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PK50 SUPEL QUE NON-BUFFERED TUBE 2 1 * 1 items
Supplier: Merck
PK50 SUPEL QUE NON-BUFFERED TUBE 2 1 * 1 items
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Tube screw 125x16mm, GPI 15-415, borosilicate. 1 * 1 items
Supplier: DWK Life Sciences
Tube screw 125x16mm, GPI 15-415, borosilicate. 1 * 1 items
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E.Z.N.A.® water DNA kit
Supplier: OMEGA BIO-TEK
The E.Z.N.A.® Water DNA kit is formulated to isolate high purity cellular DNA from water samples typically containing humic acid and inhibitors of PCR. This kit has been successfully used to isolate DNA from tough-to-lyse bacteria, fungi, and algae that inhabit a range of samples including tap water, lake, river and sewage samples. Isolated DNA can be used for most downstream applications including PCR, Southern blotting, SNP analysis.
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Gel extraction kits, E.Z.N.A.®
Supplier: OMEGA BIO-TEK
Gel purification of DNA is a common technique used for the isolation of specific DNA fragments. However, most methods either fail to completely remove agarose (which can lead to problems in downstream manipulations), shear the DNA, or result in very low yields.
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E.Z.N.A.® SP plant DNA kit
Supplier: OMEGA BIO-TEK
The E.Z.N.A.® SP plant DNA kit is specially designed for the rapid and reliable isolation of high quality total cellular DNA from a variety of plant species. Up to 100 mg of fresh samples or 30 mg of dry samples can be processed in less than 40 minutes. Purified DNA is suitable for most downstream applications including PCR, restriction digestions and hybridisation techniques.
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Bacterial RNA kit, E.Z.N.A.®
Supplier: OMEGA BIO-TEK
The E.Z.N.A.® Bacterial RNA kit is designed for isolation of high-quality total RNA from variety of bacterial strains. Up to 1×10⁹ log-phase bacterial cells can be processed. This kit uses an improved lysis procedure to ensure the complete lysis of bacterial cells. Purified RNA is suitable for downstream applications such as RT-PCR and hybridisation techniques.
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SiLibeads Typ M Kalknatron-Glaskugel, poliert, 5mm 1 * 1 kg
Supplier: SIGMUND LINDNER
SiLibeads Typ M Kalknatron-Glaskugel, poliert, 5mm 1 * 1 kg
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NEEDLE BENT POINT SMALLER TIP DIAMETER 1 * 5 items
Supplier: Hospidex
NEEDLE BENT POINT SMALLER TIP DIAMETER 1 * 5 items
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Syringe,50ul,fixed needle 100 x 0.17mm, point style 3.Hamilton. 1 * 1 items
Supplier: HAMILTON BONADUZ
Syringe,50ul,fixed needle 100 x 0.17mm, point style 3.Hamilton. 1 * 1 items
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Rotor, for holding 12tube 28x115mm, for SPD1010 and SPD2010 speedvac concentrator 1 * 1 items
Supplier: THERMO SAVANT
Rotor, for holding 12tube 28x115mm, for SPD1010 and SPD2010 speedvac concentrator 1 * 1 items
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MEAS.FLASK PACKED UNICO 10-50ML 1 * 10 items
Supplier: B. Braun
MEAS.FLASK PACKED UNICO 10-50ML 1 * 10 items
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NEEDLE REGULAR POINT 12° NORMAL TYPE 1 * 5 items
Supplier: Hospidex
NEEDLE REGULAR POINT 12° NORMAL TYPE 1 * 5 items