90560 Results for: "Okadaic+acid+ammonium+salt"

Supplier: Avantor

Powder.

Supplier: Thermo Fisher Scientific

Bathophenanthrolinedisulphonic acid disodium salt hydrate 98%

Supplier: Thermo Fisher Scientific

Bathophenanthrolinedisulphonic acid disodium salt hydrate ≥98%

Supplier: Thermo Fisher Scientific

Ammonium tetrafluoroborate ≥97%

Supplier: Thermo Fisher Scientific

4-Ethynyl-benzoic acid sodium salt 97%

Supplier: Thermo Fisher Scientific

Phenylpyruvic acid sodium salt monohydrate 98%

Supplier: Thermo Fisher Scientific

Ammonium hexafluorophosphate ≥99.5%

Supplier: Thermo Fisher Scientific

Ammonium iodide ≥98%

Supplier: Thermo Fisher Scientific

Iminodiacetic acid disodium salt hydrate 97%

Supplier: Thermo Fisher Scientific

L-Aspartic acid monosodium salt monohydrate 97%

Supplier: Thermo Fisher Scientific

D-Pantothenic acid calcium salt hydrate 98%

Supplier: Thermo Fisher Scientific

1-Hexanesulphonic acid sodium salt monohydrate ≥99%

Supplier: Cayman Chemical

ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.

Supplier: Thermo Fisher Scientific

1-Pentanesulphonic acid sodium salt monohydrate for HPLC

Supplier: Thermo Fisher Scientific

1-Octanesulphonic acid sodium salt monohydrate ≥99%

Supplier: Thermo Fisher Scientific

Ammonium chloride ≥99.5%

Supplier: Apollo Scientific

Ammonium hexafluorophosphate 99,5%

Supplier: Thermo Fisher Scientific

2-Hydroxy-2-propanesulphonic acid monosodium salt ≥97%

Supplier: Thermo Fisher Scientific

4-Chlorobenzenesulphinic acid sodium salt hydrate 97%

Supplier: VWR Chemicals

1-Butanesulphonic acid sodium salt ≥99.0% (dried basis), HiPerSolv CHROMANORM® for HPLC

Supplier: Thermo Fisher Scientific

Chromotropic acid disodium salt dihydrate ACS

Supplier: Avantor

1-Octanesulphonic acid sodium salt ≥98.0% for HPLC, for ion pair chromatography, J.T.Baker®

Supplier: Thermo Fisher Scientific

1-Octanesulphonic acid sodium salt monohydrate 98%

Supplier: Thermo Fisher Scientific

Nitrilotriacetic acid trisodium salt monohydrate ≥98%

Supplier: Thermo Fisher Scientific

Ammonium thioglycolate 70% (w/w) in water

Supplier: Thermo Fisher Scientific

L-Glutamic acid monopotassium salt monohydrate ≥97%

Supplier: Thermo Fisher Scientific

Chromotropic acid disodium salt dihydrate 98%

Supplier: Thermo Fisher Scientific

1-Hexanesulphonic acid sodium salt monohydrate 99%

Supplier: VWR Chemicals

Ammonium sulphate ≥99.5%, Proteomics Grade

Supplier: VWR Chemicals

Ammonium acetate ≥97%, GPR RECTAPUR®