19331 Results for: "Methyl+2,2-difluoropropanoate&pageNo=11&view=easy"

Supplier: Bioss

Comprising more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to APC and activates APC’s cyclin-ubiquitination activity. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC; thus preventing APC activation. APC11 is a RING-H2 finger protein that allows for the synthesis of multiubiquitin chains in the presence of Ubiquitin carrier protein 4 (Ubc4) and ubiquitin conjugating enzyme (E2). In addition, a heterodimeric complex of either Ubc4 or UbcH10 with APC11 and APC2 catalyzes the ubiquitination of human securin and cyclin B1.

Supplier: NEW PIG

Eight layers of 100% PP are thermally bonded to make PIG Mat exceptionally strong; won't rip, tear or fray even when saturated.

Supplier: GRANT INSTRUMENTS

The DEN-600 is a compact, portable, rechargeable battery powered photometer for OD600, McF turbidity and Bradford protein assay methods.

Supplier: Cytiva (Formerly Pall Lab)

A wide variety of sterile ampoule media for common microbiological analyses, in clear glass or plastic ampoules. Supplied pre-measured for maximum efficiency and convenience. For public wastewater and drinking water: MF-Endo and M-FC (with and without rosolic acid for helping to increase the specificity of the medium for faecal coliforms) media are used when analysing water samples for total coliforms, faecal coliforms and E. coli. For food and beverage: M-TGE, HPC, M-Green YM, and orange serum broths are used in the food and beverage industry to QC final products (and fluids used in the manufacture of these products) to detect potential spoilage organisms. Trypticase soy broth, M-TGE, and HPC may be used to test final products and process waters for total bacteria in the pharmaceutical and microelectronics industries. Pseudomonas and KF-Streptococcal broths are highly selective media for organisms in these genera, and are used to monitor samples wherever contamination by these organisms must be prevented.

Supplier: Thermo Fisher Scientific

Employ the most widely used MS phase in gas chromatography with the 5% phenyl phase Thermo Scientific TraceGOLD TG-5MS GC Column. These columns have exceptionally low bleed for optimal signal-to-noise ratio, sensitivity and MS integrity.

Supplier: FRISTADS KANSAS

Trousers made of 65% polyester and 35% brushed cotton. The fabric has mechanical stretch, which ensures improved comfort, especially for jobs that require a lot of movement.

Supplier: SIOEN

Water- and windproof jacket with detachable sleeves made of Siopor® Ultra fabric consisting of polyester fabric with a PU coating. With fixed quilted lining.

Supplier: Corning

Optically clear PS. Available with a choice of treated surface. Corning® CellBIND® surface increases surface wetability for more even and consistent cell attachment. Ultra-Low Attachment dishes feature a covalently bound hydrogel layer that minimises cell attachment, protein absorption and cellular activation.

Supplier: SIOEN

High visibility waistcoat made of 100% polyester with 100% FR PU-coating + AST.

Supplier: FRISTADS KANSAS

Industrial overall made of 65% polyester and 35% cotton, with soft nap on reverse side. The black overall is available with several different accent colours. The accent colour can be found on the top of the collar, on the inside front flap, on the pocket edges and and as a stripe on front and back.

Supplier: SIOEN

Flame retardant safety fleece jacket, made of 100% flame retardant polyester fleece, double-sided, with fixed flame retardant cotton lining in front.

Supplier: GA

Cryogenic direct thermal labels intended for labeling already frozen surfaces and containers under deep-freeze conditions, as low as (–80 °C).

Supplier: Brady

Mark cables and wires with the B-427 self-laminating vinyl label material, designed with a clear self-laminating protective layer. Print almost anywhere with a durable Brady portable label printer.

Supplier: Bioss

IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Supplier: Bioss

IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Supplier: SIOEN

Wind- and waterproof bodywarmer made of Flexothane® Classic: 100% polyamide knitting with PU coating. With fixed quilted lining.

Supplier: SIOEN

Comfortable, modern jacket made of 100 % quilted polyamide fabric with soft fleece lining inside and polyamide lining in the sleeves. Offers protection from wind and cold. Can be zipped in the rain jacket Tornhill (608).

Supplier: SIOEN

Waterproof and windproof rain jacket made of Flexothane Classic: 100% polyamide knitting with 100% PU coating. With high frequency welded seams.

Supplier: Portwest

The DX4 Baffle Gilet uses a body-mapped design to balance insulation and freedom of movement. Hard-wearing nylon front and back panels are padded with Insulatex to keep the core body area warm. Two zipped chest pockets, side entry pockets, and internal pockets offer plenty of secure storage space.

Supplier: Portwest

The Vision softshell is characterised by its modern, fresh design and contemporary stylish fit. The high quality 3-layer breathable, water resistant and windproof fabric along with multiple practical features ensure this is a must-have solution for a range of working professionals.

Supplier: Portwest

Portwest WX3 contemporary workwear is designed to the highest standards and offer a solution for everyday activity and working environments. Constructed with cutting edge fabrics giving superior abrasion resistance and exceptional all-day comfort. The WX3 work trousers are made from durable poly-cotton canvas fabric and includes triple stitched seams and stretch panelling providing excellent comfort and flexibility.

Supplier: Thermo Fisher Scientific

Use Thermo Scientific™ SureSTART™ 9 mm screw caps with screw vials that have a 9 mm opening, including our SureSTART 2 ml glass screw vials and 1,7 ml glass high recovery screw microvials for <2 ml samples (level 2). Select level 2 products for high-throughput applications, when robustness and reproducibility are key.

Supplier: Thermo Fisher Scientific

SureSTART™ Level 3 WebSeal™ Plate 96-well round U, V, and flat-bottom microtiter plates are designed for regulated labs that require high performing products. Level 3 well plates are for high performance applications and are suitable for regulated labs using all solvent types including non-polar solvents.

Supplier: KIMBLEKONTES

Soda lime glass, 90 expansion.

Supplier: FRISTADS KANSAS

Protective trousers made from 75% cotton and 25% polyester. The cotton/polyester fabric mix offers long lasting protection against open flames and sources of heat thanks to the flame-retardant used.

Supplier: GRANT INSTRUMENTS

The Grant Optima™ range consists of both general purpose and advanced performance thermostats combined with premium stainless steel baths (drain tap on 12, 18, 26 and 38 litre baths). Stirred circulation within the bath ensures excellent temperature stability and uniformity. Units can also be used with accessory C1G and C2G immersion coolers for operation below ambient temperatures.

Supplier: GRANT INSTRUMENTS

High quality, digital unstirred water bath range with choice of models from 2 to 34 litres and a dual bath with 5 and 12 litres. Dual baths are ideal when two different temperatures are needed and space is limited. All units have stainless steel tanks and durable painted steel cases, offer fast heat-up times, excellent temperature control, easy to use controls and a bright, clear display. All baths have heater mat technology ensuring optimum working space, without a heating element in the tank they are easier to clean. The 12 litre and larger models feature a convenient drain tap on the front of the bath. The range is ideal for use in university research and teaching, pharma/biotech, healthcare and industrial applications.

Supplier: Bioss

IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Supplier: Bioss

IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Supplier: Bioss

Comprising more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to APC and activates APC’s cyclin-ubiquitination activity. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC; thus preventing APC activation. APC11 is a RING-H2 finger protein that allows for the synthesis of multiubiquitin chains in the presence of Ubiquitin carrier protein 4 (Ubc4) and ubiquitin conjugating enzyme (E2). In addition, a heterodimeric complex of either Ubc4 or UbcH10 with APC11 and APC2 catalyzes the ubiquitination of human securin and cyclin B1.