1,1-Dimethylbiguanide hydrochloride ≥97%
Supplier: Enzo Life Sciences
Antidiabetic agent
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EX 527 ≥95%
Supplier: Enzo Life Sciences
Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM).
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Cylindrospermopsin ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Protein synthesis inhibitor
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Gramicidin A (from Bacillus brevis) ≥90% (by HPLC)
Supplier: Enzo Life Sciences
Ionophore antibiotic.
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5Z-7-Oxozeaenol (from Deuteromycetes sp.) ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Inhibitor of the JNK/p38 pathways. Inhibits anisomycin-induced but not TNF-induced JNK/p38 activation. Potent protein kinase inhibitor
>A naturally isolated cell-permeable fungal resorcylic lactone that acts as a selective and highly potent inhibitor against the MAPKKK TAK1 activity (IC50 = 8nM) in an ATP-competitive and irreversible manner; also inhibits MEK1 (IC50 = 411nM) and three other MAPKKKs (IC50 ≥268 nM against MEKK1, ASK1, and MEKK4) but at much higher concentrations. Shown to inhibit IL-1-induced/TAK1-mediated, but not H2O2-induced/TAK1-independent, JNK and p38 phosphorylation in 293 cells.
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Nadifloxacin ≥98%
Supplier: Enzo Life Sciences
Fluoroquinolone with broad spectrum activity against Gram-negative and Gram-positive bacteria. Inhibits the generation of O2- and OH radicals by neutrophils. Inhibits the production of inflammatory cytokines.
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Enniatin A (from Fusarium sp.) ≥97% (by HPLC)
Supplier: Enzo Life Sciences
White to off-white crystalline solid
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Sparfloxacin ≥98%
Supplier: Enzo Life Sciences
Fluoroquinolone with broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Inhibits bacterial DNA gyrase (topoisomerase). Effective against Mycobacterium tuberculosis. Shows photosensitizing effects.
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3,4',5,7-Tetrahydroxy-3'-methoxy flavylium chloride ≥97% (by HPLC)
Supplier: Enzo Life Sciences
Anti-inflammatory and chemopreventive. Antioxidant flavonoid.
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Methyl-6-O-(N-heptylcarbamoyl)-α-D-glucopyranoside ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Non-ionic, glucose based very mild detergent for membrane protein purification.
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DMNQ ≥99% (by TLC)
Supplier: Enzo Life Sciences
Inducer of intracellular ROS generation.
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Tin Protoporphyrin IX dichloride ≥95% (by TLC)
Supplier: Enzo Life Sciences
Potent inhibitor of heme oxygenase.
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Supplier: GRANT INSTRUMENTS
Supplier: BOCHEM
Supplier: VWR Collection
Supplier: OMEGA BIO-TEK
Supplier: DWK Life Sciences
Supplier: Thermo Fisher Scientific
Supplier: VWR Collection
Supplier: Oxford Nanopore Technologies
Supplier: Industrial Physics
Supplier: AAT BIOQUEST
Supplier: Integra
Supplier: Palbam
Supplier: VWR Collection
Supplier: Integra
Supplier: VWR Collection
Supplier: FACELLITATE
Supplier: NANOENTEK
Supplier: Greiner Bio-One