8578 Results for: "Magnesium+citrate+hydrate"
Anti-ICAM3 Mouse Monoclonal Antibody [clone: 186-2G9]
Supplier: ProSci Inc.
This antibody recognises the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM3 (Leucocyte Workshop VI). It is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This CD50 antibody is excellent for staining of formalin/paraffin tissues.
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Anti-FSHB Mouse Monoclonal Antibody [clone: FLTPb-1]
Supplier: ProSci Inc.
Follicle stimulating hormone (FSH) is a hormone synthesised and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
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Anti-ECM1 Mouse Monoclonal Antibody [clone: SRGP85]
Supplier: ProSci Inc.
Extracellular matrix protein 1 (ECM1), also called Secretory component p85, a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterised by generalized thickening of skin, mucosae and certain viscera. [RefSeq].
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Anti-EPCAM Mouse Monoclonal Antibody [clone: SPM528]
Supplier: ProSci Inc.
EGP40 is a 40-43 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
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Anti-ATF6 Mouse Monoclonal Antibody [clone: AF6229]
Supplier: ProSci Inc.
ER stress can cause the accumulation of unfolded proteins and lead to the activation of the UPR (unfolded proetin response). Cells have developed an intracellular signaling pathway to deal with this stress, and Activating Transcription Factor 6 (ATF6) is a major transducer of the UPR. Upon activation, ATF6 seperates from GPR78 and is cleaved. The ~50 kD cytosolic portion of ATF6 translocates to the nucleus, transmitting the ER stress signal. In the nucleus, ATF6 activates the transcription of UPR-responsive genes by biniding to their ERSE (ER stress response element) region.
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Anti-WT1 Rabbit Monoclonal Antibody [clone: RMWT1-1]
Supplier: ProSci Inc.
Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
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Anti-HSPB1 Mouse Monoclonal Antibody [clone: G3.1]
Supplier: ProSci Inc.
This antibody recognises a 24-27 kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). HSP27 was recently found to be identical to the estrogen-induced “p29” and “24K” protein. About 50% of breast carcinomas are positive for HSP27, especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.
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Anti-CTBP1 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for C-terminal-binding protein 1(CTBP1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
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Anti-VDAC1 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Voltage-dependent anion-selective channel protein 1(VDAC1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
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Anti-SNRPN Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Small nuclear ribonucleoprotein-associated protein N(SNRPN) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
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Anti-VCAN Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Versican core protein(VCAN) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
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Anti-AMPD3 Mouse Monoclonal Antibody [clone: ETAD3-1]
Supplier: ProSci Inc.
AMPD3 is a member of the AMP deaminase gene family. It is a highly regulated enzyme that catalyses the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in the gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. [RefSeq].
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Anti-dsDNA Mouse Monoclonal Antibody [clone: DRNC1-1]
Supplier: ProSci Inc.
Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. This mAb can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells.
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Anti-PTPRC Mouse Monoclonal Antibody [clone: PD7/26]
Supplier: ProSci Inc.
CD45RB is one of the four major isoforms of CD45. The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. Clone PD7/26 antibody is specific to CD45RB, and stains most leukemias and lymphomas. This CD45RB antibody is often used in a cocktail with clone 2B11, which will bind to all CD45 isoforms (Cat No V2243).
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Anti-MALT1 Mouse Monoclonal Antibody [clone: 4NMT-3]
Supplier: ProSci Inc.
Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition.
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Anti-ROCK2 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Rho-associated protein kinase 2(ROCK2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
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Anti-Smad2 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 2(SMAD2) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.
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Anti-Cytochrome P450 1A2 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Cytochrome P450 1A2(CYP1A2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
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HyClone Cell Boost™ 4 supplement
Supplier: HyClone products (Cytiva)
Supplements cell culture with amino acids, vitamins, glucose, trace elements, and growth factors. Manufactured to meet cGMP manufacturing standards and QC specifications.
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HyClone Cell Boost™ 3 supplement
Supplier: HyClone products (Cytiva)
Supplements cell culture with amino acids, vitamins, glucose, and trace elements and manufactured to meet cGMP manufacturing standards and QC specifications.
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Anti-Growth Hormone Mouse Monoclonal Antibody [clone: GRHP1-1]
Supplier: ProSci Inc.
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesised by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
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Carboxyl reactive biotinylation reagents, EZ-Link™
Supplier: Thermo Fisher Scientific
Carboxyl groups, in the form of carboxy termini, aspartate residues or glutamate residues, can be targeted for biotin labeling using amine-derivatised biotin molecules. This reaction is mediated by a class of crosslinkers known as carbodiimides and results in the formation of an amide bond. The reaction with EDC, the most common carbodiimide crosslinker, is generally performed in an MES buffer at pH 4,5 to 5 and requires just minutes to complete.
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Anti-ARG1 Mouse Monoclonal Antibody [clone: T1ARG-1]
Supplier: ProSci Inc.
Arginase catalyses the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterised by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [RefSeq].
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Anti-CtBP1 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for C-terminal-binding protein 1(CTBP1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
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Anti-SLC4A1 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Band 3 anion transport protein(SLC4A1) detection. Tested with WB, IHC-P, IHC-F in Human;Mouse;Rat.
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Cell culture media, powdered, Leibovitz's L-15 HyClone™
Supplier: HyClone products (Cytiva)
HyClone Leibovitz L-15 Medium is manufactured using ISO 9001:2000-certified processes
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Anti-53BP1 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Tumor suppressor p53-binding protein 1(TP53BP1) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.
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Anti-CDK1 Mouse Monoclonal Antibody [clone: CDVC2-1]
Supplier: ProSci Inc.
Cyclin-Dependent Kinase 1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. [RefSeq].
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Anti-CD68 Mouse Monoclonal Antibody [clone: CDLA68-1]
Supplier: ProSci Inc.
CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. [UniProt].
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Anti-ATXN3 Rabbit Polyclonal Antibody
Supplier: Boster Bio
Rabbit IgG polyclonal antibody for Ataxin-3(ATXN3) detection. Tested with WB, IHC-P in Human;Rat.