21985 Results for: "Fumagillin&pageNo=13&view=list"

Supplier: DUPERTHAL

Safety cabinets with storage shelves (CLASSIC line standard) or pull-out shelves (CLASSIC line pro) for the storage of hazardous substances in working spaces. Complete carcass, interior fittings and wing doors are made of powder-coated sheet steel.

Supplier: Bioss

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Supplier: Bioss

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Supplier: Bioss

PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.

Supplier: Bioss

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Supplier: VWR Collection

Pláště (opakovatelně použitelné) splňují požadavky systému HACCP a jsou vhodné pro potravinářské provozy. Jsou vyráběny z 65% polyesteru a 35% bavlny. Pláště jsou k dispozici se stojacím límečkem, s dvěma vnitřními postranními kapsami a jednou vnitřní náprsní kapsou.

Supplier: FRISTADS KANSAS

Durable jacket made of 70% polyester and 30% cotton. With several reflective stripes on shoulders, around the waist, and around the sleeves.

Supplier: FRISTADS KANSAS

Gilets made from 65% polyester and 35% cotton; napped inner.

Supplier: Spectrum Laboratories

Hollow fibre filter modules are particularly useful in tangential flow filtration because processes can easily be scaled-up from small volume applications to full-scale production.

Supplier: GA

These freezer grade blackout labels are designed to conceal any already existing information or labels. Can be used to re-label cryo vials, microtubes, and freezer boxes stored in ultra-low temperature freezers (−80 °C) or transported in dry ice.

Supplier: OHAUS

Váhy Scout® STX jsou díky snadné navigaci pomocí barevného dotykového displeje ideální volbou pro laboratorní a průmyslové aplikace, zároveň jsou díky nízkému profilu a volitelnému skladovacímu krytu nenáročné na prostor.

Supplier: Merck

BIOshell™ IgG 1000 Å C4 is a high-speed, high-performance liquid chromatography column based on a new wide-pore (1000 Å) Fused-Core® particle design.

Supplier: Biotium

MemBrite™ Fix cell surface staining kits are designed for covalently staining the surface of live cells to conveniently visualise cell boundaries in immunofluorescence experiments.

Supplier: Portwest

This jacket is made of 100% cotton with a flame-resistant finish. It offers excellent protection for welding and other allied industries.

Supplier: Agilent

GC columns achieve the highest levels of PEG stationary phase inertness performance for a range of challenging active analytes with individually-tested DB-WAX UI columns.

Supplier: Merck

BIOshell™ 160 Å Peptide CN columns provide an alternative selectivity to the traditional C18 bonded phases.

Supplier: ProSci Inc.

CHST13 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. It transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. C4ST3 transfers sulfate to the C-4 hydroxyl of beta-1,4-linked GalNAc flanked by GlcUA residues in chondroitin (Kang et al., 2002 [PubMed 12080076]).

Supplier: FRISTADS KANSAS

Jacket made of 65% polyester and 35% cotton, ideal for light-duty industrial applications. Made for the industrial worker with emphasis on comfort, durability and functionality.

Supplier: Ahlstrom-Munksjö

Ahlstrom-Munksjö’s qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers covers a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Standard qualitative filter papers are suitable for quadrant folded or gravity flow applications.

Supplier: Portwest

Wind- and water-resistant jacket made of 94% polyester and 6% Spandex laminated to a stretchable polyester fleece fabric.

Supplier: SIOEN

Bib and brace trousers with elastic braces with PVC buttons and buckles. Made of lightweight Flexothane® Essential, 100% polyester knitting with PU coating.

Supplier: MICRONOVA

The Isolator Tool™ adapter with a 360° swivel works with a range of mop covers to efficiently clean and disinfect isolators, hoods, RABS, and small equipment in clean and aseptic areas.

Supplier: Thermo Orion

The Thermo Scientific™ Orion Star™ T910 pH titrators are designed to increase your laboratory productivity by automating titrations. Our core electrochemistry technology is integrated with a state-of-the-art reagent dispensing system to create modern, simplified automated titrators designed to make performing titrations easier, more reliable and more reproducible than manual titrations.

Supplier: Avantor Fluid Handling

A highly accurate benchtop pump system for dosing, dispensing, and fill/finish applications.

Supplier: VWR Collection

ESD kalhoty jsou vyrobeny z 63% polyesteru, 35% bavlny a 2% rezistentního vlákna (uhlíku). Tato speciální směs zajišťuje stálou antistatickou ochranu. Díky tomu jsou tyto kalhoty vhodné pro použití v prostředí výroby elektroniky.

Supplier: Bioss

Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Supplier: asecos

Fireproof safety cabinets, classified type 30 (fire resistant up to 30 minutes), safe, durable, robust and convenient with transport base and bicoloured cabinet design.

Supplier: Bioss

Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).

Supplier: Bioss

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Supplier: Bioss

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].