5268 Results for: "ENZO LIFE SCIENCES"
Olomoucine ≥98%, high purity
Supplier: ENZO LIFE SCIENCES
Olomoucine is a purine derivative which acts as a potent and selective inhibitor of CDK1 (p34cdc2)/cyclin B and related kinases. It acts by competing for the ATP binding domain of the kinase. Of 35 protein kinases tested, olomoucine inhibited p33CDK2/cyclin A, p33CDK2/cyclin E, p34cdc2/cyclin B, p33CDK5/p35 and erk1 with IC50 of 7, 7, 7, 3 and 25µM respectively. The related kinases p34CDK4/cyclin D and p40CDK6/cyclin D3 were not inhibited or were less sensitive to olomoucine, IC50 > 1000 and 250µM respectively. PKC, PKA, PKG, CaM kinase II, MLC kinase, CK2, EGFR tyrosine kinase, p56lck, p56lyn, p60c-src, v-abl and insulin receptor tyrosine kinase are not inhibited or are weakly inhibited at 1mM. It delays mouse oocyte maturation and inhibits the growth of a variety of human cell lines including Rhabdomyosarcoma cell line Rh1, Rh18, Rh28 and Rh30; MCF-7, KB-3-1 and their adriamycin-resistant counterparts (IC50=18-86µM). It inhibits DNA synthesis in interleukin-2-stimulated T lymphocytes and triggers a G1 arrest similar to interleukin-2 deprivation. Can be used to synchronize cells in G1. Triggers apoptosis in target tumor cells in vitro and in vivo and in maturing cerebellar granule neurons. N9-Isopropyl-olomoucine and the negative control Iso-olomoucine are also available.
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Undeca-ubiquitin (linear)
Supplier: ENZO LIFE SCIENCES
Produced in E. coli.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
Congo red ≥95% (by HPLC), Ultrapure
Supplier: ENZO LIFE SCIENCES
beta-Amyloid dye
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Prostaglandin D₂ ≥98% (by HPLC)
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Prostanoid receptor ligand.
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(+)-cis-Diltiazem hydrochloride ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of L-type Ca²⁺ channels. Regulates Ca²⁺ release from intracellular stores in neutrophils.
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Anti-INOS Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Rabbit, Isotype: IgG
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(+)-Himbacine ≥98%, powder
Supplier: ENZO LIFE SCIENCES
Muscarinic acetylcholine receptor antagonist.
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Spermine tetrahydrochloride
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Spermine tetrahydrochloride
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PTIO (=2-phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) ≥98% (by non aqueous titration)
Supplier: ENZO LIFE SCIENCES
Stable nitric oxide (NO) radical scavenger.
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3,5,7,4'-Tetrahydroxy-3'-methoxyflavone ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Antitumor agent.
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4-Phenylchalcone oxide (synthetic) ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.
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1-Acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine (ACP)
Supplier: ENZO LIFE SCIENCES
Cell permeable probe for the detection of intracellular oxidative stress.
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p-Nitroaniline standard
Supplier: ENZO LIFE SCIENCES
pNA Calibration Standard (p-nitroaniline). Chromogenic chromophore (λmax=400nm). Reference compound.
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TRAM 34 ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
TRAM-34 is a potent and selective inhibitor of the intermediate-conductance Ca2+-activated potassium channel (IKCa). It displays immunosuppressive activity and inhibits the proliferation of endometrial cancer cells.
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Geranylgeranylpyrophosphate triammonium salt 1mg/ml ≥98%
Supplier: ENZO LIFE SCIENCES
Geranylgeranyl-donor.
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Irinotecan hydrochloride trihydrate ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Topoisomerase I inhibitor
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TMH hydrochloride
Supplier: ENZO LIFE SCIENCES
Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.
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RSSR ≥97% (by HPLC), crystalline powder
Supplier: ENZO LIFE SCIENCES
Supersensitive spin label
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TMTH hydrochloride ≥99%
Supplier: ENZO LIFE SCIENCES
Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.
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Anti-H3 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The core histones form an octamer, which is made up of one H3-H4 tetramer and two H2A-H2B dimers. The N-terminal tail of core histones undergoes different post-transcriptional modifications including acetylation, phosphorylation, methylation and ubiquitination. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression.
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Anti-Bradykinin Receptor 2 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Bradykinin (BK) is a nine-amino acid peptide produced by kallikrein cleavage of kininogen precursor proteins in tissue and plasma, and is an important regulator of vascular and pain responses to tissue injury. Two receptors (B1 and B2) have been identified as mediators of BK signaling, and are both seven-transmembrane domain-containing GPCRs. The B2 receptor is constitutively expressed in smooth muscle and neurons, whereas B1 expression is induced following injury. B2 receptors signal via Gq alpha subunits, leading to activation of phospholipase Cbeta, hydrolysis of PI, and an intracellular increase in free calcium, although coupling through Gi, Gs, and G12/13 has also been observed.
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: EPPENDORF
: Integra
: OZ BIOSCIENCES
: VWR Collection
: SenseAnywhere
: Integra
: NANOENTEK
: VWR Collection
: Integra
: Sartorius
: Quantabio