97398 Results for: "3-amino-4-(isopropylsulphonyl)thiophene-2-carboxylic+acid&pageNo=9"
CK-666 ≥95%
Supplier: Enzo Life Sciences
Cell permeable inhibitor human (IC50=4µM), fission yeast (IC50=5µM), S. cerevisiae (IC50=12µM) and bovine (IC50=17µM) Arp2/3 complex between Arp2 and Arp3. Inhibits Listeria motility (IC50=7µM).
Expand 1 Items
SB 225002 ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Chemokine receptor ligand
Expand 2 Items
TCS JNK 5a ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Thienylnaphthamide compound. Potent inhibitor of JNK2 (pIC50=6.5) and JNK3 (pIC50=6.7) targeting the ATP-binding site. Has no activity against JNK1.
Expand 1 Items
Sulindac Sulphide ≥99% (by TLC)
Supplier: Enzo Life Sciences
Active metabolite of sulindac. Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.
Expand 2 Items
ICI-118,551 ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Adrenergic receptor ligand.
Expand 1 Items
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulphonamide hydrochloride ≥98% (by TLC)
Supplier: Enzo Life Sciences
Binds to calmodulin, inhibiting Ca²⁺-calmodulin-regulated enzyme activity. It inhibits the Ca²⁺/calmodulin-induced activation of myosin light chain kinase in a concentration dependent manner (IC50=25 µM). Cell permeable.
Expand 1 Items
Mifepristone ≥99%
Supplier: Enzo Life Sciences
Progesterone receptor ligand.
Expand 2 Items
N,N-Dimethylsphingosine, D-erythro ≥98% (by TLC)
Supplier: Enzo Life Sciences
Sphingosine kinase inhibitor
Expand 2 Items
N-Hexanoyl-D-erythro-sphingosine ≥98% (by TLC)
Supplier: Enzo Life Sciences
A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.
Expand 2 Items
Phytoceramide C2 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Inhibits yeast growth and activates ceramide-activated protein phosphatase (CAPP).
Expand 1 Items
N-(2-Hydroxyethyl)oleamide ≥98% (by TLC)
Supplier: Enzo Life Sciences
Activates TRPV1. Endogenous anandamide-like lipid which regulates appetite but does not bind to cannabinoid receptors. In rats, food intake is inhibited by oral oleylethanolamide. Induces satiety by activation of PPARα. Inhibits ceramidase.
Expand 1 Items
Ono-RS-082 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Phospholipase A2 inhibitor (IC50=7 µM for purified guinea pig lung PLA2). Inhibits epinephrine-stimulated thromboxane production in human platelets (86% at 3.5µM). Also blocks insulin secretion in pancreatic islets in response to glucose. Disrupts membrane tubule-mediated reassembly and maintenance of the Golgi complex.
Expand 2 Items
CCT036477 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Disrupts Wnt signaling
Expand 2 Items
N-Arachidonoyl-serotonin ≥98% (by TLC)
Supplier: Enzo Life Sciences
TRPV1 antagonist
Expand 2 Items
WYE-125132 ≥99% (by HPLC)
Supplier: Enzo Life Sciences
Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.
Expand 2 Items
MMP-9 inhibitor I ≥97% (by HPLC)
Supplier: Enzo Life Sciences
Cell-permeable, potent, selective, and reversible MMP-9 inhibitor.
Expand 1 Items
PP242 hydrate ≥99% (by HPLC)
Supplier: Enzo Life Sciences
Inhibitor of both mTORC1 and mTORC2. Induces cell death in human and murine leukemia cells.
Expand 2 Items
SANT-1 ≥99% (by HPLC)
Supplier: Enzo Life Sciences
Potent, cell-permeable antagonist of the Shh signaling pathway.
Expand 1 Items
IC87114 ≥99% (by HPLC)
Supplier: Enzo Life Sciences
Cell permeable, selective inhibitor of PI 3-Kδ.
Expand 2 Items
GSK-3β inhibitor XVIII ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Cell-permeable, potent and selective GSK-3β inhibitor.
Expand 1 Items
Acrodisc™ PSF Non-Sterile RC Syringe Filters
Supplier: Cytiva (Formerly Pall Lab)
Acrodisc™ PSF high performance syringe filters can be used for general clarification or application specific uses like dissolution, HPLC, and IC. Engineered to work in most automated filter systems.
Expand 4 Items
9H-Fluoren-9-one oxime 5g pack 1 * 5 g
Supplier: Apollo Scientific
9H-Fluoren-9-one oxime 5g pack 1 * 5 g
Expand 1 Items
(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)propanoic acid 5g pack 1 * 5 g
Supplier: Apollo Scientific
(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)propanoic acid 5g pack 1 * 5 g
Expand 1 Items
9-([1,1'-Biphenyl]-4-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole 25g pack 1 * 25 g
Supplier: Apollo Scientific
9-([1,1'-Biphenyl]-4-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole 25g pack 1 * 25 g