100272 Results for: "3-Cyano-2,6-difluorobenzoic+acid&pageNo=10"

Supplier: ProSci Inc.

BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers. Processed human BAFF can either remain as a trimer, which is usual for TNF family ligands or assemble into 60-mer composed of 20 trimers. Mouse BAFF 60-mer has been identified in the serum of BAFF transgenic mice. Oligomerisation of BAFF 3-mer into 60-mer in human BAFF is prevented by mutation of His218, a residue critical for 3-mer-to-3-mer interactions, but not for receptor binding. Despite the predominant functional role of processed BAFF in vivo, membrane-bound BAFF might also play a role. Indeed, soluble BAFF (3-mer) can trigger BAFF-R but not TACI or BCMA, whereas oligomeric forms of BAFF (BAFF 60-mer), which mimic membrane-bound BAFF, activate all BAFF receptors.

Supplier: Abnova

Recombinant protein, hsd11b2( aah64536.1, 1 a.a. - 405 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, gabra1( np_000797.2, 1 a.a. - 456 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, chpt1( np_064629.2, 1 a.a. - 406 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, ramp1( aah00548.1, 1 a.a. - 149 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Merck

RPMI-1640 MEDIUM, MODIFIED, WITH L-GLUTAMINE, WITHOUT PHENOL RED AND SODIUM BICARBONATE. CELL CULTURE TESTED 1 * 1 Each

Supplier: Abnova

Recombinant protein, cycs( aah05299, 1 a.a. - 106 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, lgals12( aah28222, 1 a.a. - 337 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, etfdh( aah11890.1, 1 a.a. - 617 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cry1( aah30519, 1 a.a. - 587 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, il17c( np_037410.1, 1 a.a. - 197 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, atg16l1( np_110430.4, 1 a.a. - 523 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, stk32b( aah38238, 1 a.a. - 415 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, inhba( aah07858.1, 1 a.a. - 427 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, lbr( np_002287.2, 1 a.a. - 615 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cldn12( aah36754.1, 1 a.a. - 245 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, axin2( aah06295.1, 1 a.a. - 160 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, kel( np_000411.1, 1 a.a. - 732 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, bmp2( -, 1 a.a. - 396 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, gpr31( np_005290.1, 1 a.a. - 319 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, ppyr1( aah99637.1, 1 a.a. - 375 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, tmem27( np_065716.1, 1 a.a. - 222 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, irxl1( np_775847.1, 1 a.a. - 352 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, grm1( np_000829, 387 a.a. - 486 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, psmd6( np_055629, 292 a.a. - 389 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, ext2( np_000392.1, 1 a.a. - 718 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, pglyrp1( np_005082.1, 1 a.a. - 196 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, gpr12 (np_005279.1) recombinant protein without tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, opn1sw (aai56720.1) recombinant protein without tag. 1 * 2 µG

Supplier: OHAUS

Intuitive balances designed for routine weighing. Striking the ideal balance between inventive features and functional, uncomplicated weighing capabilities, the OHAUS Adventurer incorporates all of the applications necessary for routine weighing and measurement activities. With a colour touchscreen, three level user management to fulfill GLP/GMP compliance capabilities, two USB ports, and much more, Adventurer is the most complete balance in its class.