Supplier: Thermo Fisher Scientific

1,4-Naphthalenedicarboxylic acid 98+%

Supplier: Merck

1,4-Naphthalenedicarboxylic acid, Sigma-Aldrich®

Supplier: Thermo Fisher Scientific

2,6-Naphthalenedicarboxylic acid ≥98%

Supplier: Apollo Scientific

2,6-Naphthalenedicarboxylic acid 98%

Supplier: Apollo Scientific

2,7-Naphthalenedicarboxylic acid 97%

Supplier: Thermo Fisher Scientific

Dimethyl-2,6-naphthalenedicarboxylate ≥99%

Supplier: Merck

2,6-Naphthalenedicarboxylic acid, Sigma-Aldrich®

Supplier: Merck

2,6-Naphthalenedicarboxylic acid, Sigma-Aldrich®

Supplier: Merck

2,3-Naphthalenedicarboxylic acid, Sigma-Aldrich®

Supplier: Bioss

Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), but does not hydrolyse Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6.

Supplier: Bioss

Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), but does not hydrolyse Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6.

Supplier: ENZO LIFE SCIENCES

Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.

Supplier: MP Biomedicals

PGI2 is synthesized primarily in vascular endothelial cells. It is a potent inhibitor of platelet aggregation, relaxes vascular smooth muscle, and also increases cyclic AMP concentration in human platelets.

Supplier: ProSci Inc.

Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyses the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.

Supplier: ProSci Inc.

Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family. IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.

Supplier: Apollo Scientific

1,4-Phenylenediphosphonic acid

Supplier: Thermo Fisher Scientific

1,4-Phenyldiboronic acid 96%

Supplier: Apollo Scientific

1,4-Butylenediphosphonic acid

Supplier: Thermo Fisher Scientific

1,4-Benzenediacrylic acid 98%

Supplier: Apollo Scientific

1,4-Phenylenediacetic acid 97%

Supplier: Thermo Fisher Scientific

1,4-Phenylenediacetic acid ≥97%

Supplier: Thermo Fisher Scientific

1,4-Phenylenediacetic acid 97%

Supplier: Apollo Scientific

1,4-Phenyldiboronic acid

Supplier: Apollo Scientific

(R)-1,4-Benzodioxane-2-carboxylic acid 95%

Supplier: Apollo Scientific

1,4-Benzodioxane-2-carboxylic acid 98%

Supplier: Thermo Fisher Scientific

1,4-Benzodioxane-6-boronic acid 97%

Supplier: Apollo Scientific

1,4-Dimethylimidazole-5-carboxylic acid

Supplier: Apollo Scientific

1,4-Benzodioxane-6-boronic acid

Supplier: Apollo Scientific

(S)-1,4-Benzodioxane-2-carboxylic acid 95%

Supplier: Apollo Scientific

2,3-Dihydro-1,4-benzodioxine-6-carboxylic acid