48663 Results for: "1,4-Dibromonaphthalene&pageNo=8"

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12-Methoxydodecanoic acid ≥98% (by TLC)

Supplier: Enzo Life Sciences

A myristate analog which has similar chain length but reduced hydrophobicity compared to myristate. Inhibits replication of HIV-1. Its specific mechanism of action is not clear but it is believed to either inhibit the activity of N-myristoyltransferase or modulate the function of target acylated proteins.

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Simvastatin ≥98% (by TLC)

Supplier: Enzo Life Sciences

HMG-CoA reductase inhibitor

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Leukotriene E4-20,20,20-d3 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Prostanoid receptor ligand.

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N-Palmitoyl phosphatidylethanolamine ≥98% (by TLC), white solid

Supplier: Enzo Life Sciences

Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice (100 mg/kg, i.p.), without causing taste aversion. Has been found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations). This suggests that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight.

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Lysophosphatidic acid ≥98% (by TLC)

Supplier: Enzo Life Sciences

LPA receptor ligand

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EHNA ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Phosphodiesterase PDE II inhibitor, IC50=0.8 µM. Also inhibits adenosine deaminase, Ki=4 nM.

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Rolipram ≥98% (by TLC)

Supplier: Enzo Life Sciences

PDE inhibitor

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8-Methoxymethyl-IBMX ≥98% (by TLC)

Supplier: Enzo Life Sciences

Selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I, IC50=4 µM).

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Cantharidic acid ≥98% (by TLC)

Supplier: Enzo Life Sciences

PP2A inhibitor

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6-Ketoprostaglandin-F1α ≥98% (by TLC)

Supplier: Enzo Life Sciences

Biosynthesis via hydrolysis of prostacyclin. A reliable parameter for measurement of prostacyclin. Ultra-pure.

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Bufalin ≥98% (by TLC)

Supplier: Enzo Life Sciences

ATPase inhibitor

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Flumazenil ≥98%

Supplier: Enzo Life Sciences

Benzodiazepine receptor ligand.

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Cyclopiazonic acid ≥98% (by TLC)

Supplier: Enzo Life Sciences

ATPase inhibitor

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L-Mimosine ≥98%

Supplier: Enzo Life Sciences

A rare plant amino acid that reversibly blocks the cell cycle at G1-phase. Inhibits the hydroxylation of deoxyhypusine and thus inhibits eukaryote initiation factor 5-A (eIF5-A). Inhibitor of mammalian tyrosinase and dopamine β-hydroxylase. Also chelates iron via the kojic acid metal-binding domain. Arrests DNA synthesis by inhibiting deoxyribonucleotide metabolism.

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BML-210 ≥98% (by TLC)

Supplier: Enzo Life Sciences

HDAC inhibitor developed at Enzo Life Sciences. Inhibits HDAC activity in HeLa nuclear extracts (IC50=5-10µM).

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Pifithrin-α hydrobromide ≥98% (by TLC)

Supplier: Enzo Life Sciences

Chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Suppresses self-renewal of embryonic stem cells.

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12(S)-Hydroperoxyeicosa-5Z,8Z,10E,14Z-tetraenoic acid (HPETE) ≥98%

Supplier: Enzo Life Sciences

Primary metabolite of arachidonic acid via the 12-lipoxygenase pathway. Inhibits thromboxane synthase. Inhibits platelet aggregation via activation of guanylate cyclase (100% at 5µM). Stimulates leukotriene biosynthesis. Potent and selective inhibitor of Ca2+-calmodulin-dependent protein kinase II (IC50=0.7µM). Endogenous TRPV1 agonist (Ki=0.35µM).