100499 Results for: "(±)-Pipecolinic+acid&pageNo=10"

Supplier: ProSci Inc.

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. COX10 is heme A: farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: Portwest

Made from the highest quality cotton, this contemporary style offers exceptional all day comfort. Hardwearing, functional and packed full of features including: Top loading pre-shaped knee pad pockets, triple stitched seams, crotch gusset to reduce stress and prevent seam failure, adjustable leg length and a side leg cargo pocket. Strong Oxford fabric is positioned in key abrasion areas to offer extra durability.

Supplier: Ahlstrom Munksjö

PLAIN DISC GL.MICROFIBRES FILT.1,0µM25MM 1 * 50 items

Supplier: Ahlstrom Munksjö

PLAIN DISC GL.MICROFIBRES FILT.1,0µM150M 1 * 25 items

Supplier: Ahlstrom Munksjö

PLAIN DISC GL.MICROFIBRES FILT.1,0µM110M 1 * 25 items

Supplier: BUCHI

Last Flask For 5ML Ball Tube 1 * 1 items

Supplier: Testo

FILTER 325 1 * 1 items

Supplier: Sartorius Balances

The Cubis® II range has a modular design that to allows the customer to choose the components that suit the application area that is of interest. For the customer, this configurable concept delivers quality weighing, together with a high degree of flexibility, without having to invest in expensive equipment that has features that may never be required.

Supplier: Merck

FREUND'S ADJUVANT INCOMPLETE 1 * 1 Each

Supplier: Amarell

Hydrometer, DIN 12791/similar to BS 718, L20, 0,9000-0,9200:0,0002g/cm , ref. temp. 20C, without therm., 430mm long, suitable for g overnment verification 1 * 1 items

Supplier: BUCHI

Funnel for small vessels 1 * 1 items

Supplier: Testo

HPA 1 * 1 items

Supplier: Merck

PDE9A2 ACTIVE HUMAN 1 * 1 items

Supplier: SMEG

SINGLE-PHASE ELECTRIC CONNECTION 1 * 1 items

Supplier: Thermo Fisher Scientific

O-RING 2,6 X 1,3 EPDM 1 * 1 items

Supplier: Amarell

Thermometer similar to IP 44 C, solid stem, white backed, 15+121:0,5°C, red special liquid, durable pigment, suitable for government calibration 1 * 1 items

Supplier: Portwest

This jacket offers exceptional weather protection, comfort, and warmth while utilising the latest innovations in recycled fabrics. The outer shell, lining, and wadding are certified recycled polyester, and the packaging is derived from sugarcane, allowing the wearer to champion sustainability without compromising on performance.

Supplier: VACUUBRAND

Pirani-Controller CVC 3000 Set with KF DN 16, for example for RE/RZ 2.5 and RE/RZ 6 with VSP 3000, Vacuum-Valve VV-B 15C, T-Connection, SW DN 15 and more connection parts 1 * 1 SET

Supplier: BIGNEAT

HPL Flat Base, 800mm wide 1 * 1 items

Supplier: FRITSCH

Test Sieve 400/65 mm, mesh = 0.16 mm ISO 3310-1 1 * 1 items

Supplier: LABCONCO

FLUORESCENT LAMP REPLACEMENT 1 * 1 items

Supplier: Merck

TAQ DNA POLYMERASE WITH 10X REACTION 1 * 1 Each

Supplier: 3M

The 3M Speedglas Heavy-Duty Welding Helmet G5-01 builds on the 9100 series. Having more adjustable features than ever - from the colour as seen through the welding filter to the direction of the airflow and the level of coverage.

Supplier: Quantabio

Ultra-Plex™ 1-Step ToughMix® is a ready-to-use, 4X-concentrated master mix for reverse transcription quantitative PCR (RT-qPCR) of RNA templates using hybridisation probe detection chemistries such as TaqMan® 5’-hydrolysis probes on Real-Time PCR systems that utilise ROX passive reference with 490 nM excitation. First-strand cDNA synthesis and PCR amplification are carried out in the same tube without opening between procedures. It is ideal for highly sensitive quantification of RNA viruses or low abundance RNA targets in uni- or multiplexed RT-qPCR applications as well as high throughput gene-expression studies. The system has been optimised to deliver maximum RT-qPCR efficiency, sensitivity, and specificity in reduced reaction volumes and fast cycle times. Ultra-Plex™ 1-Step ToughMix® contains all required components for RT-qPCR except RNA template and probe. It is compatible with all dual-labeled probe chemistries.

Supplier: ProSci Inc.

BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers. Processed human BAFF can either remain as a trimer, which is usual for TNF family ligands or assemble into 60-mer composed of 20 trimers. Mouse BAFF 60-mer has been identified in the serum of BAFF transgenic mice. Oligomerisation of BAFF 3-mer into 60-mer in human BAFF is prevented by mutation of His218, a residue critical for 3-mer-to-3-mer interactions, but not for receptor binding. Despite the predominant functional role of processed BAFF in vivo, membrane-bound BAFF might also play a role. Indeed, soluble BAFF (3-mer) can trigger BAFF-R but not TACI or BCMA, whereas oligomeric forms of BAFF (BAFF 60-mer), which mimic membrane-bound BAFF, activate all BAFF receptors.

Supplier: TECHNI GLOVE

Nitrile GL30cmTechniGlove TN1201W tacky Size S 1 * 1.000 items

Supplier: EPPENDORF

PISTON 0,5-10UL 1 * 1 items

Supplier: DELTALAB

VACUUM PIPETTE GREEN 1 * 1 items

Supplier: Abnova

Recombinant protein, mas1 (np_002368.1) recombinant protein without tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, ccr10 (aah98132.1) recombinant protein without tag. 1 * 2 µG