- Antibody type:Primary
- Antigen name:CCR7/CD197
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Sheep,Human,Rat,Mouse
- Western blot:Yes
- Epitope:25-59/379
- Form:Liquid
- Gene ID:12775
- Antigen synonyms:MIP-3 beta receptor|Epstein-Barr virus-induced G-protein coupled receptor 1|EBV-induced G-protein coupled receptor 1|Cdw197|EBI1|Ebi1h|CCR-7|Ccr7|Cmkbr7|C-C CKR-7|CD197|CC-CKR-7|C-C chemokine receptor type 7
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:42 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from mouse CCR7
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.
Type: Primary
Antigen: CCR7/CD197
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 25-59/379
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Sheep