Anti-RCC1 Ser11 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
BOSSBS-3360R-A680
: Bioss
- Antibody type:Primary
- Antigen name:RCC1 Ser11
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Form:Liquid
- Gene ID:1104
- Antigen synonyms:Chromosome condensation 1|HERC2|RCC1_HUMAN|RanGEF|CHC 1|Cell cycle regulatory protein|RCC 1|Regulator of chromosome condensation|Chromosome condensation protein 1|Regulator of chromosome condensation 1|CHC1|SHEP1|Ran GEF|Guanine nucleotide releasing protein|RCC1 I
- Modification:Phosphorylation (Ser11)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:45 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human RCC1 around the phosphorylation site of Ser11
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis. The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin. RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, RCC1, with chromatin , but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, and, where bound, to increase the affinity of chromatin for NE membranes.
Type: Primary
Antigen: RCC1 Ser11
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human