Specifications
- Druh protilátky:Primární
- Název antigenu:DNA Polymerase lambda
- Klonovalita:Polyclonal
- Spojení:Alexa Fluor® 750
- Hostitel:Rabbit
- Imunochemie:Yes
- ImunoFluorescence:Yes
- Izotyp:IgG
- Reaktivita:Rat
- Western blot:Yes
- Epitop:475-575/575
- Formulář:Liquid
- Identifikační číslo genu:27343
- Synonyma antigenu:Pol Lambda|DNA directed DNA polymerase lambda|OTTHUMP00000020323|EC 2.7.7.7,EC 4.2.99.|BETAN|DNA polymerase beta 2|POLL|DNA polymerase beta-2|DPOLL_HUMAN|DNA polymerase kappa|POL KAPPA|POLKAPPA|DNA polymerase lambda|DNA polymerase lamda2|OTTHUMP00000059179|OTTHUMP00000020321|Pol beta2|FLJ46002|BETA N|DNA polymerase kappa DNA polymerase beta N|Polymerase DNA directed lambda
- Modifikace:Unmodified
- Skladovací pufr:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molekulární hmotnost:63 kDa
- Skladovací teplota:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Koncentrace:1 µg/µl
- Transportní teplota:4 °C
- Imunogen:KLH conjugated synthetic peptide derived from human DNA Polymerase lambda
- Testované aplikace:ICC
- Čištění:Purified by Protein A
- Typ balení:Vial
- Bal.:100 µl
Specifications
About this item
DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.
Type: Primary
Antigen: DNA Polymerase lambda
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 475-575/575
Host: Rabbit
Isotype: IgG
Reactivity: Rat