Mouse Recombinant IL-17A (Animal free) (from E. coli)

Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites. Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.

High Quality
Low Endotoxin
Affordable

A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.

: For research use only.

Spojení:
Unconjugated
Proteinový podtyp:
Cytokine
Typ proteinu/peptidu:
Recombinant
Zdroj:
E. coli
Druhy:
Mouse
Podmínky uskladnění:
–20 °C
Obsah endotoxinů:
Endotoxin LAL (EU/µg) ≤1
Biologická aktivita:
Bioactivity assay: Production of IL-6 by mouse 3T3 cells, ED50 ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
Identifikační číslo genu:
Q62386
Pokyny pro rekonstituce:
Sterile water at 0.1 mg/ml
Bez obsahu endotoxinů:
N
Bez nosiče:
Y
Bez obsahu proteázy:
N
Bez obsahu živočichů:
N
Proteinová synonyma:
IL-17|CTLA-8
Název proteinu/peptidu:
IL-17A
Čistota:
≥95%
Molekulární hmotnost:
15,1/30,2 kDa
Sekvence:
MAAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA
Úroveň endotoxinů:
Low
Formulace:
0,1% Trifluoroacetic Acid (TFA)
Bez nukleáz:
N
Třída:
RUO
Transportní teplota:
RT
Testované aplikace:
Bioassay