Human recombinant CD86 (from cells)

50 µG

Catalog # PRSI91-371

Supplier: ProSci Inc.

Catalog # PRSI91-371

Supplier: ProSci Inc.

CAS Number:

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Specifications

CAS Number:

Price

9 240,00 Kč

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Product Details & Documents

The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. The protein interacts with MARCH8， human herpesvirus 8 MIR2 protein, adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.It contains 1 Ig-like C2-type(immunoglobulin-like) domainand 1 Ig-like V-type (immunoglobulin-like) domain.

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag

Documents

Datasheet

75789-418.pdf

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Specifications

Pk:
50 µG
Protein/peptide name:
CD86
Protein synonyms:
B70|T-Lymphocyte Activation Antigen CD86|BU63|CD86|Activation B7-2 Antigen|CTLA-4 Counter-Receptor B7.2|CD28LG2|FUN-1|B7-2
Purity:
> 95% as determined by reducing SDS-PAGE
Sequence:
Ala24-Pro247
Source:
Cells
Molecular weight:
26.69 kD
Cat. No.:
PRSI91-371
Protein/peptide type:
Recombinant
Storage conditions:
Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tag sequence:
C-6 His tag
Tested applications:
For Biological Assays
Species:
Human