Human recombinant Complement Factor B (from cells)
PRSI91-305
:
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:Cells
- Species:Human
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Protein synonyms:BFD|Glycine-Rich Beta Glycoprotein|Properdin Factor B|GBG|Complement Factor B|BF|PBF2|C3/C5 Convertase|CFB
- Protein/peptide name:Complement Factor B
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:84.07 kD
- Sequence:Thr26-Leu764
- Formulation:Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag