Human recombinant PDGF-BB (from E. coli)

PRSI91-179

PRSI91-179

Pk:
50 µG
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Protein synonyms:
SIS|PDGF2|Platelet-Derived Growth Factor B Chain|Platelet-Derived Growth Factor Subunit B|Proto-Oncogene c-Sis|PDGF Subunit B|PDGFB|Platelet-Derived Growth Factor Beta Polypeptide|Becaplermin|PDGF-2
Protein/peptide name:
PDGF-BB
Purity:
> 95% as determined by reducing SDS-PAGE
Molecular weight:
12.42 kD
Sequence:
Ser82-Thr190
Formulation:
Lyophilized from a 0.2 um filtered solution of 4mM HCl. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested applications:
Bioassay

Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

This recombinant protein can be used for biological assays. For research use only.