- Antigen name:Death Domain-Containing protein
- Antigen symbol:CRADD
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Antigen synonyms:RAIDD|MRT34|CASP2 and RIPK1 domain containing adaptor with death domain
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:RAIDD antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human RAIDD.
- Tested applications:E, WB, IHC
- Purification:DEAE purified
- Size:100 µg
- Pk:100 µG
RAIDD Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1, RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.
Type:
Antigen: CRADD
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: