This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Type: Primary
Antigen: VEGFA
Clonality: Monoclonal
Clone: VEGF/1063
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Dog, Human, Mouse, Rabbit, Rat
- Catalog No:
- BNC041063-500
- BNC041063-100
- Antigen symbol:
- VEGFA
- VEGFA
- Antigen name:
- Vascular endothelial growth factor A
- Vascular endothelial growth factor A
- Antigen synonyms:
- Vascular Endothelial Growth Factor A (VEGF-A)|MVCD1|VEGFA|Vascular Permeability Factor (VPF)
- Vascular Endothelial Growth Factor A (VEGF-A)|MVCD1|VEGFA|Vascular Permeability Factor (VPF)
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 405S
- CF® 405S
- Clone:
- Clone VEGF/1063
- Clone VEGF/1063
- Reactivity:
- Rabbit, Human, Dog, Rat, Mouse
- Rabbit, Human, Dog, Rat, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 73793
- 73793
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide