Specifikace
- Antibody type:Primary
- Antigen name:CD20
- Antigen symbol:MS4A1
- Clonality:Monoclonal
- Clone:Clone 93-1B3
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoFluorescence:Yes
- Isotype:IgG1 kappa
- Reactivity:Human
- Gene ID:712553
- Storage buffer:PBS/0,05% azide
- Concentration:1 mg/mL
- Purification:BSA-free
- Size:50 μL
- Pk:50 µl
Specifikace
O tomto produktu
Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.4). It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.
Type: Primary
Antigen: MS4A1
Clonality: Monoclonal
Clone: 93-1B3
Conjugation: Purified, BSA-free
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human