Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.
Type: Primary
Antigen: ITGAL
Clonality: Monoclonal
Clone: DF1524
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human
- Catalog No:
- BNC680312-100
- BNC680312-500
- Antigen symbol:
- ITGAL
- ITGAL
- Antigen name:
- CD11a
- CD11a
- Antigen synonyms:
- p180|LFA 1 alpha (LFA1A)|ITGAL|Antigen CD11A (p180)|Ly21|Integrin alpha-L|Ly15|lymphocyte function associated antigen 1|alpha polypeptide|Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain
- p180|LFA 1 alpha (LFA1A)|ITGAL|Antigen CD11A (p180)|Ly21|Integrin alpha-L|Ly15|lymphocyte function associated antigen 1|alpha polypeptide|Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 568
- CF® 568
- Clone:
- Clone DF1524
- Clone DF1524
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 174103
- 174103
- Isotype:
- IgG2b kappa
- IgG2b kappa
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Chemicals
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection