Recognizes a protein of 55 kDa, identified as CD25 (Workshop IV; Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R beta chain, p75) and CD132 (common gammachain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.
Type: Primary
Antigen: IL2RA
Clonality: Monoclonal
Clone: 143-13
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
- Catalog No:
- BNCB0297-500
- BNCB0297-100
- Antigen symbol:
- IL2RA
- IL2RA
- Antigen name:
- CD25
- CD25
- Antigen synonyms:
- IL2R alpha chain|T Cell Growth Factor Receptor|TCGFR|Ly43|p55|IL2 Receptor alpha|p55 chain|IL2R|TAC antigen|Interleukin-2 receptor subunit alpha|IL2R subunit alpha IL2RA
- IL2R alpha chain|T Cell Growth Factor Receptor|TCGFR|Ly43|p55|IL2 Receptor alpha|p55 chain|IL2R|TAC antigen|Interleukin-2 receptor subunit alpha|IL2R subunit alpha IL2RA
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- Biotin
- Biotin
- Clone:
- Clone 143-13
- Clone 143-13
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 231367
- 231367
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection
: KIMBERLY CLARK
: VWR Collection