Specifications
- Antibody type:Primary
- Antigen name:Protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
- Antigen symbol:PTPN13
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Form:liquid
- Gene ID:5783
- Antigen synonyms:PTP-E1|protein tyrosine phosphatase 1E|PTP-BL|hPTPE1|PTP1E|APO-1/CD95 (Fas)-associated phosphatase|PNP1|FAP-1|PTP-BAS|fas-associated protein-tyrosine phosphatase 1|DKFZp686J1497|tyrosine-protein phosphatase non-receptor type 13|protein-tyrosine phosphatase 1|nonreceptor type 13|protein-tyrosine phosphatase PTPL1|PTPLE|PTPL1|Fas-associated phosphatase-1|protein tyrosine phosphatase|protein-tyrosine phosphatase 1E|Fas-associated
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Concentration:1 ug/ul
- Shipping temperature:4 °C
- Purification:Purified by Protein A.
- Size:100 μg
- Pk:100 µl
Specifications
About this item
PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: PTPN13
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat