Anti-CD178 (Fas ligand) Mouse Antibody (In Vivo Ready™) [clone: NOK-1]
40-9919-U100
- Antibody type:Primary
- Antigen name:Fas Ligand
- Antigen symbol:FASLG
- Clone:NOK-1
- Flow cytometry:Yes
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Neutralisation:Yes
- Gene ID:356
- Antigen synonyms:APT1LG1|APTL|TNFSF6|CD178|FASL|ALPS1B|CD95-L|CD95L
- Storage temperature:Store undiluted at 2-8 °C, protect from light, do not freeze.
- Size:100 μg
- Pk:100 µG
The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
Type: Primary
Antigen: CD178 (Fas ligand)
Clonality:
Clone: NOK-1
Conjugation: In Vivo Ready™
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human