Gliotoxin
Gliotoxin (from Gladiocladium fimbriatum) ≥97% (by HPLC, TLC)
Supplier: Enzo Life Sciences
Immunomodulating mycotoxin which acts by blocking membrane thiol groups. Inhibits the chymotrypsin-like activity of the 20S proteasome in a non-competitive manner. Causes apoptotic cell death in macrophages and thymocytes. Induces Ca2+ release from intact rat liver mitochondria. Inhibits the activation of transcription factor NF-κB in response to a variety of stimuli in T and B cells. Displays anti-inflammatory activity in vivo. Antioxidant. Inhibitor of farnesyltransferase and geranylgeranyltransferase I. A negative control analog is available. Displays anti-tumor activity against breast cancer in vivo.
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Gliotoxin (from Gliocladium fimbriatum)
Supplier: Apollo Scientific
Gliotoxin, gladiocladium fimbriatum (from Gliocladium fimbriatum)
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