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Ascomycin (from Streptomyces species) ≥90% (by HPLC, TLC)
Supplier: ENZO LIFE SCIENCES
Ascomycin is a close structural analog of FK506 and is a potent immunosuppressant. It binds to FKBP (FK506-binding protein) and suppresses its proline rotamase activity. The ascomycin-FKBP complex inhibits calcineurin, a type 2B phosphatase.
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Ascomycin 95%
Supplier: Thermo Fisher Scientific
An analog of tacrolimus (FK-506). Ascomycin is an inhibitor of PP2 and it is potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases.
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