Anti-CMYA2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog # BOSSBS-9477R-A680

Supplier: Bioss

Catalog # BOSSBS-9477R-A680

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
CMYA2
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 680
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Epitope:
1501-1600/2365
Form:
Liquid
Gene ID:
9659
Antigen synonyms:
MMGL|MYOME_HUMAN|CMYA2|Cardiomyopathy associated protein 2|Cardiomyopathy-associated protein 2|Pde4dip|Phosphodiesterase 4D interacting protein|Myomegalin|Phosphodiesterase 4D-interacting protein
Modification:
Unmodified
Storage buffer:
Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Storage temperature:
Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Concentration:
1 µg/µl
Shipping temperature:
4 °C
Immunogen:
KLH conjugated synthetic peptide derived from human CMYA2/PDE4DIP
Purification:
Purified by Protein A
Pack type:
Vial
Pk:
100 µl

Specifications

About this item

May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes. Myomegalin, is a 2346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events.

Type: Primary
Antigen: CMYA2
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 1501-1600/2365
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat