5269 Results for: "Enzo Life Sciences"
(±)4-Hydroxydebrisoquin ≥99%, white solid
Supplier: Enzo Life Sciences
Major metabolite of debrisoquin.
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ML-9 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Selective inhibitor of MLC kinase (Ki=3.8 µM). Inhibits insulin-stimulated 2-deoxyglucose transport and PP-1 activation in adipocytes, possibly via an effect on MAP kinase or its activation. Useful PKB inhibitor (IC50=10-50 µM). Also known to inhibit PKA (IC50=20 µM) and S6 kinase (IC50=50 µM). Does not inhibit PI 3-kinase.
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3-Methylcyclopentadecanone ≥99% (by TLC), colourless oil
Supplier: Enzo Life Sciences
Induces rat liver microsomal cytochrome P-450.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
SB202190 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis.
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H-89 dihydrochloride ≥99% (by TLC)
Supplier: Enzo Life Sciences
Protein kinase inhibitor
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AG-494 ≥98% (by TLC)
Supplier: Enzo Life Sciences
AG-494 is a member of the tyrphostin family of tyrosine kinase inhibitors and is a potent inhibitor of EGF receptor autophosphorylation (IC50=1.2 µM) and EGF-dependent cell growth (IC50=6 µM). It selectively inhibits HER1 (EGF receptor) vs. HER1-2 receptor autophosphorylation (HER1: IC50=1.1 µM; HER1-2: IC50=45 µM). HER1-2 is a chimeric receptor consisting of the external HER1 domain fused to an internal HER2 domain. Blocks CDK2 activation and causescells to arrest at late G1 and during S phase.
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Herbimycin A ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Antibiotic. Cell permeable tyrosine kinase inhibitor. It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products and inhibits thrombin-induced tyrosine phosphorylation of phospholipase C. It also inhibits HSP90, NF-κB activation and angiogenesis. Increases the sensitivity of certain cancer cells to chemotherapeutic agents. Blocks mitotic activity. Neurotoxic.
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Cinnamyl-3,4-dihydroxy-α-cyanocinnamate ≥98%
Supplier: Enzo Life Sciences
Lipoxygenase inhibitor
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Tyrphostin A23 ≥99% (by TLC)
Supplier: Enzo Life Sciences
A potent inhibitor of EGF receptor kinase activity (IC50=35 µM).
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(±)-S-Nitroso-N-acetylpenicillamine (SNAP) ≥98% (by TLC)
Supplier: Enzo Life Sciences
Stable analog of endogenous S-nitroso compounds. Nitric oxide (NO) donor and a source of NO in vivo which spontaneously releases NO under physiological conditions. The half-life time is 4.6 hours in aqueous media.
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8-Bromo-cAMP sodium salt ≥98% (by HPLC)
Supplier: Enzo Life Sciences
PKA activator.
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Mdivi -1 ≥97% (by HPLC)
Supplier: Enzo Life Sciences
Mdivi-1 is a selective inhibitor of mitochondrial division in yeast and mammalian cells which acts via inhibiting the mitochondrial division dynamin. In cells, Mdivi-1 inhibits apoptosis by inhibiting mitochondrial outer membrane permeabilization. Mdivi-1 causes the rapid (50= ~10µM. In yeast, time-lapse fluorescence microscopy revealed no detectable mitochondrial division after treatment with Mdivi-1. It inhibits Dnm1 GTPase activity in a dose dependent manner with an estimated IC50 of 1-10µM but is not a general inhibitor of GTPases.
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GW5074 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Potent and selective cell permeable inhibitor of cRAF1 kinase (IC50 = 9 nM) with 100-fold selectivity over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. A useful tool for assessing the involvement of the Ras/Raf-1/ERK pathway in various signaling pathways. Displays neuroprotective effects in vivo through a MEK-ERK and Akt-independent mechanism.
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DMOG ≥99% (by TLC)
Supplier: Enzo Life Sciences
DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models. DMOG also inhibits FIH (Factor Inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/kg). Is expected to act pro-angiogenic.
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Acitretin ≥98% (by TLC)
Supplier: Enzo Life Sciences
Retinoic acid receptor ligand.
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Docosa-7Z,10Z,13Z,16Z,19Z-pentaenoic acid ≥98%
Supplier: Enzo Life Sciences
Polyunsaturated fatty acid.
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Methanandamide ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cannabinoid receptor ligand
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VAS-2870 ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Novel inhibitor of NAD(P)H oxidase (Nox). In vascular smooth muscle cells VAS-2870 completely abolished PDGF-mediated NAD(P)H oxidase activation and ROS production (100% at 10µM). It inhibits PDGF-induced chemotaxis but not proliferation of VSMC. In mouse embryonic stem cells VAS-2870 blocked PDGF-BB-induced vasculogenesis. OxLDL-induced ROS formation in human endothelial cells was completely inhibited by VAS-2870 (100% at 5µM). VAS-2870 inhibits PMS-induced oxidative burst in HL-60 cells (IC50=2µM).
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Supplier: GRANT INSTRUMENTS
Supplier: BOCHEM
Supplier: VWR Collection
Supplier: OMEGA BIO-TEK
Supplier: Liebherr
Supplier: DWK Life Sciences
Supplier: Thermo Fisher Scientific
Supplier: VWR Collection
Supplier: Oxford Nanopore Technologies
Supplier: Industrial Physics
Supplier: AAT BIOQUEST
Supplier: Integra
Supplier: Palbam
Supplier: VWR Collection
Supplier: Integra
Supplier: VWR Collection
Supplier: FACELLITATE
Supplier: NANOENTEK
Supplier: Greiner Bio-One