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5268 results for "ENZO LIFE SCIENCES"

5268 výsledků pro: "ENZO LIFE SCIENCES"

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Pig recombinant NGAL (pig)

Supplier: ENZO LIFE SCIENCES

Produced in E. coli.

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Human MMP2 proenzyme (from fibroblasts)

Supplier: ENZO LIFE SCIENCES

Isolated from human rheumatoid synovial fibroblasts. Requires activation.

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PP2 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Src kinase inhibitor

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Corning Life Sciences

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Anti-Complement C5B-9 Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES

C5b-9, also known as the terminal complement complex (TCC), consists of C5b, C6, C7, C8 and C9, and it forms the membrane attack complex (MAC) as well as the non-lytic fluid-phase SC5b-9 complex (with protein S). The MAC forms channels in target cell membranes leading to cell lysis by osmotic leakage. The complexes contain neoantigens absent from the individual native components from which they are formed, and the antibody is directed against a neoepitope exposed on C9 when incorporated into the TCC.

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([K48-only]Ub)n-ubiquitinylated Substrate

Supplier: ENZO LIFE SCIENCES

Protein components produced in E. coli. Synthesized enzymatically in vitro. (K48-only)Ubn-ubiquitinylated substrate protein was produced using K48-only mutant ubiquitin.

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Muscimol ≥98% (by TLC)

Muscimol ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Potent GABAA receptor agonist.

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Pertussis Toxin (Bordetella pertussis)

Pertussis Toxin (Bordetella pertussis)

Supplier: ENZO LIFE SCIENCES

Ultra-pure

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Ras inhibitory peptide

Supplier: ENZO LIFE SCIENCES

The peptide sequence corresponds to amino acid residues 1149-1158 of the guanine nucleotide-releasing factor hSos1, which is essential for the control of Ras activity. Blocks the binding of hSos1 to human Grb2, a protein that binds to activated receptor tyrosine kinases.

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Pyocyanin ≥98% (by HPLC)

Pyocyanin ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

ROS inducer.

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Docosa-7Z,10Z,13Z,16Z,19Z-pentaenoic acid ≥98%

Docosa-7Z,10Z,13Z,16Z,19Z-pentaenoic acid ≥98%

Supplier: ENZO LIFE SCIENCES

Polyunsaturated fatty acid.

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PNU-74654 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Catenin blocker

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Cinnamyl-3,4-dihydroxy-α-cyanocinnamate ≥98%

Supplier: ENZO LIFE SCIENCES

Lipoxygenase inhibitor

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Anti-USP19 Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES

Anti-USP19 Rabbit Polyclonal Antibody

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Anti-SAP97 Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES

Synapse-associated proteins SAP97 and SAP102 display extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminals. In addition to the CNS, SAP97 is also detected at the basal lateral membrane between a variety of epithelial cells. SAP102 associates with NMDA receptors through the C-terminal NR2B subunit of the receptor. The N-terminal SAP97 PDZ domain mediates its interaction with the synaptic ras-GTPase activating protein SynGAP.

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Anti-p47Phox, NCF1 Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES

Anti-p47Phox, NCF1 Rabbit Polyclonal Antibody

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ODN 1585 (synthetic), TLRgrade™

Supplier: ENZO LIFE SCIENCES

TLR9 ligand.

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Anti-LCN2 Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES

Rat lipocalin-2 is also called rat NGAL, as it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL). Rat NGAL is a 25-kDa alpha 2-microglobulin-related protein or neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including cells of the renal proximal tubules. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is upregulated in a variety of pathological situations including infection, inflammation, ischemia-reperfusion and in certain adenocarcinomas.

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6-(Benzyloxy)-7H-purin-2-amine ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

DNA alkyltransferase substrate and inhibitor

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Human recombinant yellow fever NS1

Supplier: ENZO LIFE SCIENCES

Yellow Fever virus NS1 protein presented in its native folded state with all post-translational modifications to deliver optimal antigenicity.

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Anti-TRAIL-R2 Mouse Monoclonal Antibody [clone: DJR2-2]

Supplier: ENZO LIFE SCIENCES

DR5 is a 55kDa member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.

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Adenosine 5'-diphosphate disodium salt (ADP disodium salt)

Supplier: ENZO LIFE SCIENCES

Adenosine 5'-diphosphate disodium salt (ADP disodium salt)

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Anti-MDA5 Mouse Monoclonal Antibody [clone: 1B6]

Supplier: ENZO LIFE SCIENCES

MDA5 is a highly conserved helicase whose ATPase activity can be stimulated by RNA and less potently by DNA. It contains two N-terminal CARD domains and a C-terminal helicase domain. The helicase domain, once freed from the CARD domains, then translocates from the cytoplasm to the nucleus where it acts on chromatin architecture. This could allow easier access of CAD, thereby accelerating the degradation of genomic DNA.

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Anti-HSP90 Mouse Monoclonal Antibody (DyLight® 488)

Supplier: ENZO LIFE SCIENCES

The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

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Anti-Endothelin B Receptor Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES

Endothelins are vasoactive peptides that exist in three forms (ET-1, ET-2, and ET-3), and function in the maintenance of vascular tone via two identified seven transmembrane-spanning domain-containing G protein-coupled receptors (GPCR), endothelin A (ETA) and endothelin B (ETB). The human ETA receptor is primarily expressed in vascular smooth muscle cells, including those of the heart (also in myocytes), lung, and brain, and its stimulation generally results in vasoconstriction. Activation of ETA receptors can be stimulated by binding of ET-1 and ET-2, but not ET-3. triggering the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells. Human ETB receptors are primarily expressed in endothelial cells lining the vessel walls of the lungs, heart, and brain, and in contrast to ETA receptors, stimulation generally results in transient vasodilation. Activation of ETB receptors can be stimulated by binding of all three endothelins, triggering the release of vasorelaxive

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ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na2, oxidized form)

Supplier: ENZO LIFE SCIENCES

ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na2, oxidized form)

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Anti-ENOS Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES

Host: Rabbit

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Human recombinant IL-13

Supplier: ENZO LIFE SCIENCES

Produced in E. coli.

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Bilobalide ≥98% (by HPLC), white solid

Bilobalide ≥98% (by HPLC), white solid

Supplier: ENZO LIFE SCIENCES

Bilobalide is a terpenoid isolated from Ginkgo biloba. It has been proposed to exert trophic and protective effects on neurons. It increases the sensitivity of mouse pancreatic β cells to glucose and displays protective effects during hypoxia.

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Abz-FRK(Dnp)-P

Supplier: ENZO LIFE SCIENCES

ACE substrate

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Aflatoxin M1 ≥95% (by HPLC, TLC)

Supplier: ENZO LIFE SCIENCES

Hepatotoxic and hepatocarcinogenic mycotoxin.

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