316 výsledků pro: "Charles River Laboratories Cell Solutions"

Supplier: Charles River Laboratories Cell Solutions

Human serum, hepatitis B virus (HBV)

Supplier: Charles River Laboratories Cell Solutions

Human plasma, colorectal cancer (CRC)

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Human mononuclear cells from breast cancer (BC)

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Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of human immunodeficiency virus (HIV). Collected from IRB-consented donors diagnosed with HIV.

Supplier: Charles River Laboratories Cell Solutions

CryoStor® cryopreservation freeze media products have been designed to mitigate temperature-induced molecular cell stress responses during freezing and thawing.

Supplier: Charles River Laboratories Cell Solutions

A Leukopak is an enriched leukapheresis product collected from normal peripheral blood. It is composed of a variety of blood cells including monocytes, lymphocytes, platelets, plasma, and red cells. A leukopak contains a higher concentration of cells as compared to standard venipuncture collection methods or buffy coat products.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood CD14⁺ monocytes are isolated from peripheral blood mononuclear cells (PBMCs) by either positive or negative selection using immunomagnetic cell separation procedures. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.

Supplier: Charles River Laboratories Cell Solutions

Naive T cells are isolated by depleting CD45RO^₊ cells via immunomagnetic bead separation from a freshly collected leukopheresis product. Naive T cells are phenotypically classified as CD45⁺, CD^₊, and CD45RA^₊.

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CD8⁺ cytotoxic T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.

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CD4⁺/CD25⁺ regulatory T cells were isolated from leukapheresis product by CD127 depletion and positive selection using CD25 immunomagnetic beads. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells are isolated from IRB-consented volunteer donors diagnosed with HIV or AIDS.

Supplier: Charles River Laboratories Cell Solutions

Mononuclear cells used for researching the causes, diagnosis, supportive care and treatment of Diabetes Mellitus 2 (DM2), the most common form of diabetes. Human mononuclear cells are collected from human volunteer donors diagnosed with DM2 under IRB approved informed consent by whole blood or leukapheresis using the COBE® Spectra Apheresis System MNC collection protocol.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of Crohn's disease (CD). Collected from IRB-consented donors diagnosed with CD.

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Human mononuclear cells, rheumatoid arthritis (RA)

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Human serum, systemic lupus erythematosus (SLE)

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CD34⁺ cells are isolated using positive immunomagnetic cell separation procedures from umbilical cord blood. Human cord blood is collected aseptically at the time of delivery from healthy pregnant women under institutional review board (IRB) approved procedures.

Supplier: Charles River Laboratories Cell Solutions

CD34 depleted mononuclear cells from mobilised peripheral blood are isolated by depleting the CD34 cells using immunomagnetic anti-CD34 microbeads.

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Bone marrow is a major source of stem cells, which are being used in cancer research, cell studies, transplantation studies, and other research.

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Mesenchymal stem cells (MSC) are cultured from freshly collected adult human bone marrow. MSCs are isolated by adherence from bone marrow mononuclear cells, isolated using a density gradient. Adherent cells were cultured in MEM-alpha, supplemented with L-glutamine and Human Platelet Lysate. Bone marrow aspirate is collected from healthy human volunteer donors under IRB approved informed consent and drawn from the posterior iliac crest using a syringe containing anticoagulant.

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Human peripheral blood M2 macrophages are derived from purified monocytes. CD14⁺ monocytes were positively selected via immunomagnetic beads and were cultured in the presence of M-CSF for 10 days. The M2 phenotyping was confirmed by morphology and the expression of specific biomarkers which monitored by flow cytometry. The cells were harvested after 10 days of in vitro culture.

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Human mononuclear cells, multiple myeloma

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Human serum, chronic lymphocytic leukemia (CLL)

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Ulcerative colitis (UC) is isolated from mononuclear cells collected from IRB-consented donors diagnosed with ulcerative colitis (UC).

Supplier: Charles River Laboratories Cell Solutions

Mononuclear cells are critical components of the immune system which are involved in both humoral and cell-mediated immunity. The mononuclear cell is a widely used product in research and clinical applications such as in microbiology, virology, oncology, vaccine development, transplant and regenerative biology, and toxicology.

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Human peripheral blood M1 macrophages are derived from purified monocytes. CD14⁺ monocytes were isolated from peripheral blood mononuclear cells (PBMCs) using positive immunomagnetic cell separation procedures and were cultured in the presence of GM-CSF for 10 days. The M1 phenotyping was confirmed by morphology and the expression of specific biomarkers.

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Psoriasis (PSO) is isolated from mononuclear cells collected from IRB-consented donors diagnosed with psoriasis (PSO).

Supplier: Charles River Laboratories Cell Solutions

Human serum used for researching the causes, diagnosis, supportive care and treatment of hepatitis C Virus (HCV). Collected from IRB-consented donors diagnosed with HCV.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of multiple sclerosis (MS). Collected from IRB-consented donors diagnosed with MS.

Supplier: Charles River Laboratories Cell Solutions

Human plasma, systemic lupus erythematosus (SLE)

Supplier: Charles River Laboratories Cell Solutions

Plasma used for researching the causes, diagnosis, supportive care and treatment of gastric cancer (GC). Patient samples can be used by researchers to investigate biomarker and diagnostic development, pre-clinical research validation, and drug toxicity and efficacy. Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of gastric cancer (GC). Collected from IRB-consented donors diagnosed with GC.