Human Recombinant IL-21 (CTGrade GMP) (from E. coli)

New Product

New Product

About this item

PDGF-BB (Platelet-derived growth factor) comprises a family of homo or heterodimeric growth factors, including PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD. Binds to two different transmembrane tyrosine kinase receptors (PDGFR-alpha and PDFGR-beta). Released from degranulating platelets and plays a role in each stage of wound healing. Stimulates mitogenicity and chemotaxis of neutrophils, macrophages, fibroblasts, and smooth muscle cells to the wound site.

High quality
Low endotoxin
Lot-to-lot consistency
Animal free
Manufactured following GMP guidelines

Enhances proliferation of fibroblasts and their production of extracellular matrix. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.

Host cell protein: ≤30 ng/ml
Host cell DNA: ≤0,01 ng/ml
Sterility testing: No growth
Mycoplasma: Negative

Caution: For research use or further manufacturing only.

Specifications

Spojení:
Unconjugated
Proteinový podtyp:
Cytokine
Typ proteinu/peptidu:
Recombinant
Zdroj:
E. coli
Druhy:
Human
Podmínky uskladnění:
At or below −20 °C
Obsah endotoxinů:
Endotoxin LAL (EU/µg) ≤0.05
Biologická aktivita:
Bioactivity assay: Proliferation of B9 cell, ED50 ≤5 ng/ml, bioactivity ≥WHO standard not available
Identifikační číslo genu:
Q9HBE4
Pokyny pro rekonstituce:
Sterile water at 0,1 - 0,5 mg/ml
Bez obsahu endotoxinů:
N
Bez nosiče:
Y
Bez obsahu proteázy:
N
Bez obsahu živočichů:
Y
Čistota:
≥97%
Molekulární hmotnost:
15,4 kDa
Sekvence:
MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSANTG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIHQ HLSSRTHGSE DS
Úroveň endotoxinů:
Low
Formulace:
10 mM sodium phosphate, pH 7,5
Bez nukleáz:
N
Třída:
GMP
Transportní teplota:
Ambient
Testované aplikace:
Bioassay