IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells. Signals through a receptor complex containing two receptors, IL-6Rα and gp130. Plays an important function in promoting fever and can serve to stimulate an immune response to trauma.
- High quality
- Low endotoxin
- Lot-to-lot consistency
- Animal free
- Manufactured following GMP guidelines
IL-6 is often used for growth of hybridoma cell lines. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Host cell protein: ≤30 ng/ml
Host cell DNA: ≤0,01 ng/ml
Sterility testing: No growth
Mycoplasma: Negative
- Spojení:Unconjugated
- Proteinový podtyp:Cytokine
- Typ proteinu/peptidu:Recombinant
- Zdroj:E. coli
- Druhy:Human
- Podmínky uskladnění:At or below −20 °C
- Obsah endotoxinů:Endotoxin LAL (EU/µg) ≤0.05
- Biologická aktivita:Bioactivity assay: Proliferation of OCI-Aml5, ED50 ≤5 ng/ml, bioactivity ≥1,6×10³ IU/µg
- Identifikační číslo genu:P49771
- Pokyny pro rekonstituce:Sterile water at 0,1 - 0,5 mg/ml
- Bez obsahu endotoxinů:N
- Bez nosiče:Y
- Bez obsahu proteázy:N
- Bez obsahu živočichů:Y
- Proteinová synonyma:Flt3L|Fms-related tyrosine kinase 3 ligand
- Čistota:≥97%
- Molekulární hmotnost:17,7 kDa
- Sekvence:MTQDCSFQHS PISSDFAVKI RELSDYLLQD YPVTVASNLQ DEELCGGLWR LVLAQRWMER LKTVAGSKMQ GLLERVNTEI HFVTKCAFQP PPSCLRFVQT NISRLLQETS EQLVALKPWI TRQNFSRCLE LQCQPDSSTL PPPWSPRPLE ATAPT
- Úroveň endotoxinů:Low
- Formulace:10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- Bez nukleáz:N
- Třída:GMP
- Transportní teplota:Ambient
- Testované aplikace:Bioassay
: RATIOLAB
: EPPENDORF
: witeg Labortechnik
: Corning
: VWR Collection
: Whatman products (Cytiva)
: Bel-Art Products, a Part of SP
: Simport Scientific
: Corning