About this item
SCF is a multipotent factor which affects cells of the myeloid, erythroid, mast, and lymphoid lineages.
- High quality
- Low endotoxin
- Lot-to-lot consistency
- Animal free
- Manufactured following GMP guidelines
Exists both as a membrane-bound and soluble form
Expressed by fibroblasts and endothelial cells promoting proliferation, migration, survival, and differentiation in hematopoietic progenitors, melanocytes, and germ cells
Promotes mast cell secretory function, chemotaxis, and adhesion
Enhances secretion of mediators in response to IgE-dependent activation
The biological activity of CTGrade GMP interleukins and growth factors is standardised, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance
Host Cell Protein: ≤30 ng/ml
Host Cell DNA: ≤0,01 ng/ml
Sterility testing: No Growth
Mycoplasma: Negative
Specifications
- Spojení:Unconjugated
- Proteinový podtyp:Cytokine
- Typ proteinu/peptidu:Recombinant
- Zdroj:E. coli
- Druhy:Human
- Podmínky uskladnění:At or below –20 °C
- Obsah endotoxinů:Endotoxin LAL (EU/µg) ≤0,05
- Biologická aktivita:Bioactivity Assay: Proliferation of TF-1, ED₅₀ ≤15 ng/ml, Bioactivity ≥1,0x10³ IU/µg
- Identifikační číslo genu:P21583
- Pokyny pro rekonstituce:Sterile water at 0,1 - 0,5 mg/ml
- Bez obsahu endotoxinů:N
- Bez nosiče:Y
- Bez obsahu proteázy:N
- Bez obsahu živočichů:Y
- Proteinová synonyma:c-Kit Ligand|KL|mgF|Steel Factor
- Název proteinu/peptidu:CTGrade GMP SCF
- Čistota:≥97%
- Molekulární hmotnost:18,6 kDa
- Sekvence:MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA
- Úroveň endotoxinů:Low
- Formulace:10 mM Sodium phosphate, 50 mM Sodium chloride, pH 7,5
- Bez nukleáz:N
- Třída:GMP
- Transportní teplota:Ambient
- Testované aplikace:Bioassay